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1Z93
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HUMAN CARBONIC ANHYDRASE III:STRUCTURAL AND KINETIC STUDY OF CATALYSIS AND PROTON TRANSFER.
分子名称:Carbonic anhydrase III, ZINC ION
著者Duda, D.M., Tu, C., Fisher, S.Z., An, H., Yoshioka, C., Govindasamy, L., Laipis, P.J., Agbandje-McKenna, M., Silverman, D.N., McKenna, R.
登録日2005-03-31
公開日2005-08-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
1Z97
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HUMAN CARBONIC ANHYDRASE III: STRUCTURAL AND KINETIC STUDY OF CATALYSIS AND PROTON TRANSFER.
分子名称:Carbonic anhydrase III, ZINC ION
著者Duda, D.M., Tu, C., Fisher, S.Z., An, H., Yoshioka, C., Govindasamy, L., Laipis, P.J., Agbandje-McKenna, M., Silverman, D.N., McKenna, R.
登録日2005-03-31
公開日2005-08-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
1YO0
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PROTON TRANSFER FROM HIS200 IN HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase II, ZINC ION, CHLORIDE ION
著者Bhatt, D., Tu, C., Fisher, S.Z., Hernandez Prada, J.A., McKenna, R., Silverman, D.N.
登録日2005-01-26
公開日2005-09-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Proton transfer in a Thr200His mutant of human carbonic anhydrase II
Proteins, 61, 2005
1YO1
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PROTON TRANSFER FROM HIS200 IN HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase II, SULFATE ION, ZINC ION
著者Bhatt, D., Tu, C., Fisher, S.Z., Hernandez Prada, J.A., McKenna, R., Silverman, D.N.
登録日2005-01-26
公開日2005-09-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Proton transfer in a Thr200His mutant of human carbonic anhydrase II
Proteins, 61, 2005
1YO2
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PROTON TRANSFER FROM HIS200 IN HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase II, ZINC ION
著者Bhatt, D., Tu, C., Fisher, S.Z., Hernandez Prada, J.A., McKenna, R., Silverman, D.N.
登録日2005-01-26
公開日2005-09-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Proton transfer in a Thr200His mutant of human carbonic anhydrase II
Proteins, 61, 2005
1XV8
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CRYSTAL STRUCTURE OF HUMAN SALIVARY ALPHA-AMYLASE DIMER
分子名称:Alpha-amylase, CALCIUM ION, CHLORIDE ION
著者Fisher, S.Z., Govindasamy, L., Tu, C.K., Silverman, D.N., Rajaniemi, H., McKenna, R.
登録日2004-10-27
公開日2005-10-11
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Human Salivary Alpha-Amylase Dimer
To be Published
2AX2
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PRODUCTION AND X-RAY CRYSTALLOGRAPHIC ANALYSIS OF FULLY DEUTERATED HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase II, ZINC ION
著者Budayova-Spano, M., Fisher, S.Z., Dauvergne, M.T., Silverman, D.N., Myles, D.A.A., McKenna, R.M.
登録日2005-09-02
公開日2006-01-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II.
Acta Crystallogr.,Sect.F, 62, 2006
2ANL
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X-RAY CRYSTAL STRUCTURE OF THE ASPARTIC PROTEASE PLASMEPSIN 4 FROM THE MALARIAL PARASITE PLASMODIUM MALARIAE BOUND TO AN ALLOPHENYLNORSTATINE BASED INHIBITOR
分子名称:plasmepsin IV, (4R)-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamide
著者Clemente, J.C., Govindasamy, L., Madabushi, A., Fisher, S.Z., Moose, R.E., Yowell, C.A., Hidaka, K., Kimura, T., Hayashi, Y., Kiso, Y., Agbandje-McKenna, M., Dame, J.B., Dunn, B.M., McKenna, R.
登録日2005-08-11
公開日2006-04-04
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor.
Acta Crystallogr.,Sect.D, 62, 2006
2EU2
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HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, (R)-1-AMINO-1-[5-(DIMETHYLAMINO)-1,3,4-THIADIAZOL-2-YL]METHANESULFONAMIDE
著者Fisher, S.Z., Govindasamy, L., Boyle, N., Agbandje-McKenna, M., Silverman, D.N., Blackburn, G.M., McKenna, R.
登録日2005-10-28
公開日2006-07-11
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes.
Acta Crystallogr.,Sect.F, 62, 2006
2EU3
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HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, 1-(5-AMINO-1,3,4-THIADIAZOL-2-YL)-1,1-DIFLUOROMETHANESULFONAMIDE
著者Fisher, S.Z., Govindasamy, L., Boyle, N., Agbandje-McKenna, M., Silverman, D.N., Blackburn, G.M., McKenna, R.
登録日2005-10-28
公開日2006-07-11
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes.
Acta Crystallogr.,Sect.F, 62, 2006
2FNK
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ACTIVATION OF HUMAN CARBONIC ANHYDRASE II BY EXOGENOUS PROTON DONORS
分子名称:Carbonic anhydrase 2, ZINC ION
著者Bhatt, D., Fisher, S.Z., Tu, C., McKenna, R., Silverman, D.N.
登録日2006-01-11
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Location of binding sites in small molecule rescue of human carbonic anhydrase II.
Biophys.J., 92, 2007
2FNM
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ACTIVATION OF HUMAN CARBONIC ANHDYRASE II BY EXOGENOUS PROTON DONORS
分子名称:carbonic anhydrase 2, ZINC ION
著者Bhatt, D., Fisher, S.Z., Tu, C., McKenna, R., Silverman, D.N.
登録日2006-01-11
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Location of binding sites in small molecule rescue of human carbonic anhydrase II.
Biophys.J., 92, 2007
2FNN
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ACTIVATION OF HUMAN CARBONIC ANHYDRASE II BY EXOGENOUS PROTON DONORS
分子名称:Carbonic Anhydrase 2, ZINC ION, 4-METHYLIMIDAZOLE
著者Bhatt, D., Fisher, S.Z., Tu, C., McKenna, R., Silverman, D.N.
登録日2006-01-11
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Location of binding sites in small molecule rescue of human carbonic anhydrase II.
Biophys.J., 92, 2007
2NWO
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STRUCTURAL AND KINETIC EFFECT OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-16
公開日2007-04-24
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NWP
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION, SULFATE ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-16
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NWY
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS ON THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-16
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NWZ
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS ON THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION, SULFATE ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-16
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NXR
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STRUCTURAL EFFECTS OF HYDROPHOBIC MUTATIONS ON THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION, SULFATE ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-19
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NXS
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION, SULFATE ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-19
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NXT
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-19
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2HFW
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STRUCTURAL AND KINETIC ANALYSIS OF PROTON SHUTTLE RESIDUES IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE III
分子名称:Carbonic anhydrase 3, ZINC ION
著者Elder, I., Fisher, S.Z., Laipis, P.J., Tu, C.K., McKenna, R., Silverman, D.N.
登録日2006-06-26
公開日2007-05-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase III.
Proteins, 68, 2007
2ILI
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REFINE ATOMIC STRUCTURE OF HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z.
登録日2006-10-02
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism
Biochemistry, 46, 2007
2OSM
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INHIBITION OF CARBONIC ANHYDRASE II BY THIOXOLONE: A MECHANISTIC AND STRUCTURAL STUDY
分子名称:Carbonic anhydrase 2, ZINC ION, 2-MERCAPTOPHENOL
著者Albert, A.B., Caroli, G., Govindasamy, L., Agbandje-Mckenna, M., McKenna, R., Tripp, B.C.
登録日2007-02-06
公開日2008-02-12
最終更新日2012-12-26
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of Carbonic Anhydrase II by Thioxolone: A Mechanistic and Structural Study.
Biochemistry, 47, 2008
2QWS
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NEUTRON AND X-RAY STRUCTURAL STUDIES OF SHORT HYDROGEN BONDS IN PHOTOACTIVE YELLOW PROTEIN (PYP)
分子名称:Photoactive yellow protein, 4'-HYDROXYCINNAMIC ACID
著者Fisher, S.Z., Langan, P.
登録日2007-08-10
公開日2008-03-18
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Neutron and X-ray structural studies of short hydrogen bonds in photoactive yellow protein (PYP)
Acta Crystallogr.,Sect.D, 63, 2007
2OSF
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INHIBITION OF CARBONIC ANHYDRASE II BY THIOXOLONE: A MECHANISTIC AND STRUCTURAL STUDY
分子名称:Carbonic anhydrase 2, ZINC ION, 4-MERCAPTOBENZENE-1,3-DIOL, ...
著者Albert, A.B., Caroli, G., Govindasamy, L., Agbandje-McKenna, M., McKenna, R., Tripp, B.C.
登録日2007-02-05
公開日2008-05-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of carbonic anhydrase II by thioxolone: a mechanistic and structural study.
Biochemistry, 47, 2008