4Q49
Room temperature neutron crystal structure of apo human carbonic anhydrase at pH 7.5
Summary for 4Q49
Entry DOI | 10.2210/pdb4q49/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION (3 entities in total) |
Functional Keywords | mixed alpha beta, proton transfer, cytosolic, lyase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 29354.47 |
Authors | Fisher, S.Z.,McKenna, R. (deposition date: 2014-04-14, release date: 2015-02-25, Last modification date: 2023-09-20) |
Primary citation | Michalczyk, R.,Unkefer, C.J.,Bacik, J.P.,Schrader, T.E.,Ostermann, A.,Kovalevsky, A.Y.,McKenna, R.,Fisher, S.Z. Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer. Proc.Natl.Acad.Sci.USA, 112:5673-5678, 2015 Cited by PubMed: 25902526DOI: 10.1073/pnas.1502255112 PDB entries with the same primary citation |
Experimental method | NEUTRON DIFFRACTION (1.8 Å) |
Structure validation
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