6FJJ
Joint neutron and x-ray crystal structure of human carbonic anhydrase IX mimic (saccharin).
Summary for 6FJJ
Entry DOI | 10.2210/pdb6fjj/pdb |
Related | 6fji |
Descriptor | Carbonic anhydrase 2, ZINC ION, 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, ... (4 entities in total) |
Functional Keywords | joint x-ray neutron diffraction, carbonic anhydrase, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29449.48 |
Authors | Fisher, S.Z. (deposition date: 2018-01-22, release date: 2019-02-06, Last modification date: 2024-05-01) |
Primary citation | Koruza, K.,Mahon, B.P.,Blakeley, M.P.,Ostermann, A.,Schrader, T.E.,McKenna, R.,Knecht, W.,Fisher, S.Z. Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative. J. Struct. Biol., 205:147-154, 2019 Cited by PubMed: 30639924DOI: 10.1016/j.jsb.2018.12.009 PDB entries with the same primary citation |
Experimental method | NEUTRON DIFFRACTION (2 Å) X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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