4Y0J

H/D exchanged human carbonic anhydrase II pH 6 room temperature neutron crystal structure.

Summary for 4Y0J

Entry DOI	10.2210/pdb4y0j/pdb
Descriptor	Carbonic anhydrase 2, ZINC ION (3 entities in total)
Functional Keywords	neutron, proton transfer, h/d exchanged, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	29136.19
Authors	Fisher, S.Z. (deposition date: 2015-02-06, release date: 2015-04-22, Last modification date: 2024-01-10)
Primary citation	Michalczyk, R.,Unkefer, C.J.,Bacik, J.P.,Schrader, T.E.,Ostermann, A.,Kovalevsky, A.Y.,McKenna, R.,Fisher, S.Z. Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer. Proc.Natl.Acad.Sci.USA, 112:5673-5678, 2015 Cited by PubMed: 25902526 DOI: 10.1073/pnas.1502255112 PDB entries with the same primary citation
Experimental method	NEUTRON DIFFRACTION (2 Å)

Structure validation