Author results

1FQ3
  • Download 1fq3
  • View 1fq3
Molmil generated image of 1fq3
CRYSTAL STRUCTURE OF HUMAN GRANZYME B
Descriptor:GRANZYME B, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Estebanez-Perpina, E., Fuentes-Prior, P., Belorgey, D., Rubin, H., Bode, W.
Deposit date:2000-09-03
Release date:2001-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.
Biol.Chem., 381, 2000
1JQG
  • Download 1jqg
  • View 1jqg
Molmil generated image of 1jqg
CRYSTAL STRUCTURE OF THE CARBOXYPEPTIDASE A FROM HELICOVERPA ARMIGERA
Descriptor:carboxypeptidase A, ZINC ION
Authors:Estebanez-Perpina, E., Bayes, A., Vendrell, J., Jongsma, M.A., Bown, D.P., Gatehouse, J.A., Huber, R., Bode, W., Aviles, F.X., Reverter, D.
Deposit date:2001-08-07
Release date:2002-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera.
J.Mol.Biol., 313, 2001
1MZA
  • Download 1mza
  • View 1mza
Molmil generated image of 1mza
CRYSTAL STRUCTURE OF HUMAN PRO-GRANZYME K
Descriptor:pro-granzyme K
Authors:Hink-Schauer, C., Estebanez-Perpina, E., Wilharm, E., Fuentes-Prior, P., Klinkert, W., Bode, W., Jenne, D.E.
Deposit date:2002-10-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The 2.2-A Crystal Structure of Human Pro-granzyme K Reveals a Rigid Zymogen with Unusual Features
J.BIOL.CHEM., 277, 2002
1MZD
  • Download 1mzd
  • View 1mzd
Molmil generated image of 1mzd
CRYSTAL STRUCTURE OF HUMAN PRO-GRANZYME K
Descriptor:pro-granzyme K
Authors:Hink-Schauer, C., Estebanez-Perpina, E., Wilharm, E., Fuentes-Prior, P., Klinkert, W., Bode, W., Jenne, D.E.
Deposit date:2002-10-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The 2.2-A Crystal Structure of Human Pro-granzyme K Reveals a Rigid Zymogen with Unusual Features
J.BIOL.CHEM., 277, 2002
1OP8
  • Download 1op8
  • View 1op8
Molmil generated image of 1op8
CRYSTAL STRUCTURE OF HUMAN GRANZYME A
Descriptor:Granzyme A, SULFATE ION
Authors:Hink-Schauer, C., Estebanez-Perpina, E., Bode, W., Jenne, D.
Deposit date:2003-03-05
Release date:2003-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the apoptosis-inducing human granzyme A dimer
NAT.STRUCT.BIOL., 10, 2003
1T5Z
  • Download 1t5z
  • View 1t5z
Molmil generated image of 1t5z
CRYSTAL STRUCTURE OF THE ANDROGEN RECEPTOR LIGAND BINDING DOMAIN (LBD) WITH DHT AND A PEPTIDE DERIVED FROM ITS PHYSIOLOGICAL COACTIVATOR ARA70
Descriptor:Androgen receptor, Nuclear receptor coactivator 4, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Estebanez-Perpina, E., Moore, J.M.R., Mar, E., Nguyen, P., Delgado-Rodrigues, E., Baxter, J.D., Webb, P., Fletterick, R.J., Guy, R.K.
Deposit date:2004-05-05
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor.
J.Biol.Chem., 280, 2005
1T63
  • Download 1t63
  • View 1t63
Molmil generated image of 1t63
CRYSTAL STRUCTURE OF THE ANDROGEN RECEPTOR LIGAND BINDING DOMAIN WITH DHT AND A PEPTIDE DERIVED FROM ITS PHYSIOLOGICAL COACTIVATOR GRIP1 NR BOX3
Descriptor:Androgen receptor, Nuclear receptor coactivator 2, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Estebanez-Perpina, E., Moore, J.M.R., Mar, E., Nguyen, P., Delgado-Rodrigues, E., Baxter, J.D., Webb, P., Fletterick, R.J., Guy, R.K.
Deposit date:2004-05-05
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor.
J.Biol.Chem., 280, 2005
1T65
  • Download 1t65
  • View 1t65
Molmil generated image of 1t65
CRYSTAL STRUCTURE OF THE ANDROGEN RECEPTOR LIGAND BINDING DOMAIN WITH DHT AND A PEPTIDE DERIVED FORM ITS PHYSIOLOGICAL COACTIVATOR GRIP1 NR BOX 2 BOUND IN A NON-HELICAL CONFORMATION
Descriptor:Androgen receptor, Nuclear receptor coactivator 2, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Estebanez-Perpina, E., Moore, J.M.R., Mar, E., Nguyen, P., Delgado-Rodrigues, E., Baxter, J.D., Webb, P., Fletterick, R.J., Guy, R.K.
Deposit date:2004-05-05
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor.
J.Biol.Chem., 280, 2005
1XJ7
  • Download 1xj7
  • View 1xj7
Molmil generated image of 1xj7
COMPLEX ANDROGEN RECEPTOR LBD AND RAC3 PEPTIDE
Descriptor:Androgen receptor, RAC3 derived peptide, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Estebanez-Perpina, E., Moore, J.M.R., Mar, E., Nguyen, P., Delgado-Rodrigues, E., Baxter, J.D., Buehrer, B.M., Webb, P., Fletterick, R.J., Guy, R.K.
Deposit date:2004-09-22
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor
J.Biol.Chem., 280, 2005
2PIN
  • Download 2pin
  • View 2pin
Molmil generated image of 2pin
THYROID RECEPTOR BETA IN COMPLEX WITH INHIBITOR
Descriptor:Thyroid hormone receptor beta-1, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID, 1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE, ...
Authors:Estebanez-Perpina, E., Jouravel, N., Baxter, J.D., Guy, L.R., Webb, P., Fletterick, R.J.
Deposit date:2007-04-13
Release date:2008-02-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor.
Mol.Endocrinol., 21, 2007
2PIO
  • Download 2pio
  • View 2pio
Molmil generated image of 2pio
ANDROGEN RECEPTOR LBD WITH SMALL MOLECULE
Descriptor:Androgen receptor, SULFATE ION, 5-ALPHA-DIHYDROTESTOSTERONE, ...
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Deposit date:2007-04-13
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PIP
  • Download 2pip
  • View 2pip
Molmil generated image of 2pip
ANDROGEN RECEPTOR LBD WITH SMALL MOLECULE
Descriptor:Androgen receptor, SULFATE ION, 5-ALPHA-DIHYDROTESTOSTERONE, ...
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Deposit date:2007-04-13
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PIQ
  • Download 2piq
  • View 2piq
Molmil generated image of 2piq
ANDROGEN RECEPTOR LBD WITH SMALL MOLECULE
Descriptor:Androgen receptor, SULFATE ION, 5-ALPHA-DIHYDROTESTOSTERONE, ...
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Deposit date:2007-04-13
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PIR
  • Download 2pir
  • View 2pir
Molmil generated image of 2pir
ANDROGEN RECEPTOR LBD WITH SMALL MOLECULE
Descriptor:Androgen receptor, SULFATE ION, 5-ALPHA-DIHYDROTESTOSTERONE, ...
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Deposit date:2007-04-13
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PIT
  • Download 2pit
  • View 2pit
Molmil generated image of 2pit
ANDROGEN RECEPTOR LBD WITH SMALL MOLECULE
Descriptor:Androgen receptor, SULFATE ION, 5-ALPHA-DIHYDROTESTOSTERONE, ...
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Deposit date:2007-04-13
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PIU
  • Download 2piu
  • View 2piu
Molmil generated image of 2piu
ANDROGEN RECEPTOR LBD WITH SMALL MOLECULE
Descriptor:Androgen receptor, 5-ALPHA-DIHYDROTESTOSTERONE, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Deposit date:2007-04-13
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PIV
  • Download 2piv
  • View 2piv
Molmil generated image of 2piv
ANDROGEN RECEPTOR WITH SMALL MOLECULE
Descriptor:Androgen receptor, SULFATE ION, 5-ALPHA-DIHYDROTESTOSTERONE, ...
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Deposit date:2007-04-13
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PIW
  • Download 2piw
  • View 2piw
Molmil generated image of 2piw
ANDROGEN RECEPTOR WITH SMALL MOLECULE
Descriptor:Androgen receptor, 5-ALPHA-DIHYDROTESTOSTERONE, 3,5,3'TRIIODOTHYRONINE
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Deposit date:2007-04-13
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PIX
  • Download 2pix
  • View 2pix
Molmil generated image of 2pix
AR LBD WITH SMALL MOLECULE
Descriptor:Androgen receptor, 5-ALPHA-DIHYDROTESTOSTERONE, 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Deposit date:2007-04-13
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PKL
  • Download 2pkl
  • View 2pkl
Molmil generated image of 2pkl
ANDROGEN RECEPTOR LBD WITH SMALL MOLECULE
Descriptor:Androgen receptor, ARA70 peptide, 5-ALPHA-DIHYDROTESTOSTERONE, ...
Authors:Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Guy, K.R., Webb, P., Fletterick, R.J.
Deposit date:2007-04-17
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QPY
  • Download 2qpy
  • View 2qpy
Molmil generated image of 2qpy
AR LBD WITH SMALL MOLECULE
Descriptor:Androgen receptor, Coactivator peptide, 5-ALPHA-DIHYDROTESTOSTERONE, ...
Authors:Estebanez-Perpina, E., Fletterick, R.
Deposit date:2007-07-25
Release date:2007-09-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3BKI
  • Download 3bki
  • View 3bki
Molmil generated image of 3bki
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH FQX AT 1.87 ANGSTROMS
Descriptor:Glutamate receptor 2, [1,2,5]oxadiazolo[3,4-g]quinoxaline-6,7(5H,8H)-dione 1-oxide
Authors:Cruz, L., Estebanez-Perpina, E., Pfaff, S., Borngraeber, S., Bao, N., Fletterick, R., England, P.
Deposit date:2007-12-06
Release date:2008-09-16
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) forms an irreversible bond to the active site of the GluR2 AMPA receptor.
J.Med.Chem., 51, 2008
5JJM
  • Download 5jjm
  • View 5jjm
Molmil generated image of 5jjm
CRYSTAL STRUCTURE OF HOMODIMERIC ANDROGEN RECEPTOR LIGAND-BINDING DOMAIN BOUND TO DHT AND LXXLL PEPTIDE
Descriptor:Androgen receptor, Unknown peptide, uba3-derived peptide, ...
Authors:Estebanez-Perpina, E., Fuentes-Prior, P.
Deposit date:2016-04-24
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of the homodimeric androgen receptor ligand-binding domain.
Nat Commun, 8, 2017