1MZA

crystal structure of human pro-granzyme K

Summary for 1MZA

• Entry DOI: 10.2210/pdb1mza/pdb
• Related: 1MZD
• Descriptor: pro-granzyme K (2 entities in total)
• Functional Keywords: granzyme, apoptosis, serine protease, s1 family, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P49863
• Total number of polymer chains: 1
• Total formula weight: 26134.19

Authors

Hink-Schauer, C.,Estebanez-Perpina, E.,Wilharm, E.,Fuentes-Prior, P.,Klinkert, W.,Bode, W.,Jenne, D.E. (deposition date: 2002-10-07, release date: 2003-01-14, Last modification date: 2024-04-03)

• Primary citation: Hink-Schauer, C.,Estebanez-Perpina, E.,Wilharm, E.,Fuentes-Prior, P.,Klinkert, W.,Bode, W.,Jenne, D.E.; The 2.2-A Crystal Structure of Human Pro-granzyme K Reveals a Rigid Zymogen with Unusual Features; J.BIOL.CHEM., 277:50923-50933, 2002; PubMed: 12384499; DOI: 10.1074/jbc.M207962200

Experimental method

X-RAY DIFFRACTION (2.23 Å)