Crystal Structure of Homodimeric Androgen Receptor Ligand-Binding Domain bound to DHT and LxxLL peptide

Summary for 5JJM

DescriptorAndrogen receptor, Unknown peptide, uba3-derived peptide, ... (13 entities in total)
Functional Keywordsnuclear receptor, transcription factor, oxosteroid receptor, human androgen receptor, transcription
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  P10275 P10275
Total number of polymer chains12
Total molecular weight125816.63
Estebanez-Perpina, E.,Fuentes-Prior, P. (deposition date: 2016-04-24, release date: 2017-03-15)
Primary citation
Nadal, M.,Prekovic, S.,Gallastegui, N.,Helsen, C.,Abella, M.,Zielinska, K.,Gay, M.,Vilaseca, M.,Taules, M.,Houtsmuller, A.B.,van Royen, M.E.,Claessens, F.,Fuentes-Prior, P.,Estebanez-Perpina, E.
Structure of the homodimeric androgen receptor ligand-binding domain.
Nat Commun, 8:14388-14388, 2017
PubMed: 28165461 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms14388
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24250.1%4.4%0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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