5JJM
Crystal Structure of Homodimeric Androgen Receptor Ligand-Binding Domain bound to DHT and LxxLL peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, D | Androgen receptor | polymer | 252 | 29406.5 | 3 | UniProt (P10275) Pfam (PF00104) In PDB | Homo sapiens (Human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
2 | M, F, K, L | Unknown peptide | polymer | 3 | 379.4 | 4 | Homo sapiens (Human) | ||
3 | B | Androgen receptor | polymer | 252 | 29435.5 | 1 | UniProt (P10275) Pfam (PF00104) In PDB | Homo sapiens (Human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
4 | G, H, I, J | uba3-derived peptide | polymer | 8 | 936.1 | 4 | UniProt (by SIFTS) (Q8TBC4) In PDB | Homo sapiens (Human) | |
5 | D, A, B, C | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 4 | Chemie (DHT) | |||
6 | C, D, A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
7 | D, A, B | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
8 | C, D, A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
9 | C, A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
10 | C, D, A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | Homo sapiens (Human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 | |
11 | C | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
12 | D | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
13 | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 122916.6 | |
Non-Polymers* | Number of molecules | 28 |
Total formula weight | 2900.0 | |
All* | Total formula weight | 125816.6 |