5JJM

Crystal Structure of Homodimeric Androgen Receptor Ligand-Binding Domain bound to DHT and LxxLL peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, G (A, C, D)	Androgen receptor	polymer	252	29406.5	3	UniProt (P10275) Pfam (PF00104)	Homo sapiens (Human)	Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4
2	B, D, F, H (M, F, K, L)	Unknown peptide	polymer	3	379.4	4		Homo sapiens (Human)
3	C (B)	Androgen receptor	polymer	252	29435.5	1	UniProt (P10275) Pfam (PF00104)	Homo sapiens (Human)	Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4
4	I, J, K, L (G, H, I, J)	uba3-derived peptide	polymer	8	936.1	4	UniProt (by SIFTS) (Q8TBC4)	Homo sapiens (Human)
5	HA, M, S, Z (D, A, B, C)	5-ALPHA-DIHYDROTESTOSTERONE	non-polymer		290.4	4	Chemie (DHT)
6	AA, GA, N, T (C, D, A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
7	IA, O, U (D, A, B)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
8	BA, JA, KA, MA, P... (C, D, A, B)	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
9	CA, Q (C, A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
10	EA, FA, NA, R, Y (C, D, A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)	Homo sapiens (Human)	Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4
11	DA (C)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
12	LA (D)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
13	OA, PA, QA, RA (A, B, C, D)	water	water		18.0	99	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	122916.6
Non-Polymers*	Number of molecules	28
	Total formula weight	2900.0
All*	Total formula weight	125816.6

*Water molecules are not included.