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5JJM

Crystal Structure of Homodimeric Androgen Receptor Ligand-Binding Domain bound to DHT and LxxLL peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, DAndrogen receptorpolymer25229406.53UniProt (P10275)
Pfam (PF00104)
In PDB
Homo sapiens (Human)Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4
2M, F, K, LUnknown peptidepolymer3379.44Homo sapiens (Human)
3BAndrogen receptorpolymer25229435.51UniProt (P10275)
Pfam (PF00104)
In PDB
Homo sapiens (Human)Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4
4G, H, I, Juba3-derived peptidepolymer8936.14UniProt (by SIFTS) (Q8TBC4)
In PDB
Homo sapiens (Human)
5D, A, B, C5-ALPHA-DIHYDROTESTOSTERONEnon-polymer290.44Chemie (DHT)
6C, D, A, BZINC IONnon-polymer65.44Chemie (ZN)
7D, A, BCHLORIDE IONnon-polymer35.53Chemie (CL)
8C, D, A, B1,2-ETHANEDIOLnon-polymer62.18Chemie (EDO)
9C, AGLYCEROLnon-polymer92.12Chemie (GOL)
10C, D, A, BSULFATE IONnon-polymer96.15Chemie (SO4)Homo sapiens (Human)Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4
11CTRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
12DACETATE IONnon-polymer59.01Chemie (ACT)
13waterwater18.099Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight122916.6
Non-Polymers*Number of molecules28
Total formula weight2900.0
All*Total formula weight125816.6
*Water molecules are not included.

221716

PDB entries from 2024-06-26

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