5JJM
Crystal Structure of Homodimeric Androgen Receptor Ligand-Binding Domain bound to DHT and LxxLL peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, G (A, C, D) | Androgen receptor | polymer | 252 | 29406.5 | 3 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (Human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| 2 | B, D, F, H (M, F, K, L) | Unknown peptide | polymer | 3 | 379.4 | 4 | Homo sapiens (Human) | ||
| 3 | C (B) | Androgen receptor | polymer | 252 | 29435.5 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (Human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| 4 | I, J, K, L (G, H, I, J) | uba3-derived peptide | polymer | 8 | 936.1 | 4 | UniProt (by SIFTS) (Q8TBC4) | Homo sapiens (Human) | |
| 5 | HA, M, S, Z (D, A, B, C) | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 4 | Chemie (DHT) PubChem (16395945) PubChem (1779160) PubChem (15) PubChem (10635) PubChem (147320) PubChem (23729584) PubChem (44264584) PubChem (44307156) PubChem (44308180) PubChem (44314545) PubChem (1779165) PubChem (1779163) PubChem (44403751) PubChem (667503) PubChem (928651) PubChem (54132599) PubChem (57253355) PubChem (67080676) PubChem (2748143) PubChem (68213431) PubChem (70627790) PubChem (76333143) PubChem (6432518) PubChem (11302) PubChem (7052570) PubChem (7052571) PubChem (90350225) PubChem (9965809) PubChem (10379482) PubChem (10902374) PubChem (968803) PubChem (11860392) PubChem (11867857) PubChem (11867858) PubChem (11867859) PubChem (11867860) PubChem (11869358) PubChem (11869359) PubChem (11869361) PubChem (11914201) PubChem (11920866) PubChem (12446746) PubChem (12446747) PubChem (12446748) PubChem (12446749) PubChem (12446752) PubChem (6951009) PubChem (124916763) PubChem (133612463) PubChem (11869360) PubChem (124305346) PubChem (124335861) PubChem (124350819) PubChem (124362930) PubChem (124402106) PubChem (124420348) PubChem (124907326) PubChem (124907327) PubChem (16111632) PubChem (134753818) PubChem (139564330) PubChem (141909893) PubChem (142776876) PubChem (145087815) PubChem (156740897) PubChem (162854571) PubChem (162854572) PubChem (162854573) PubChem (164663566) PubChem (165146196) PubChem (165431280) | |||
| 6 | AA, GA, N, T (C, D, A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 7 | IA, O, U (D, A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) PubChem (312) | |||
| 8 | BA, JA, KA, MA, P... (C, D, A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 9 | CA, Q (C, A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 10 | EA, FA, NA, R, Y (C, D, A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | Homo sapiens (Human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 | |
| 11 | DA (C) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 12 | LA (D) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 13 | OA, PA, QA, RA (A, B, C, D) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 122916.6 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 2900.0 | |
| All* | Total formula weight | 125816.6 |
