Author results

4ZDR
  • Download 4zdr
  • View 4zdr
Molmil generated image of 4zdr
CRYSTAL STRUCTURE OF 14-3-3[ZETA]-LKB1 FUSION PROTEIN
Descriptor:14-3-3 protein zeta/delta,GGSGGS linker,Serine/threonine-protein kinase STK11, GLYCEROL, SULFATE ION, ...
Authors:Ding, S., Shi, Z.B.
Deposit date:2015-04-18
Release date:2015-09-09
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Structure of the 14-3-3[zeta]-LKB1 fusion protein provides insight into a novel ligand-binding mode of 14-3-3
Acta Crystallogr.,Sect.F, 71, 2015
5WXN
  • Download 5wxn
  • View 5wxn
Molmil generated image of 5wxn
STRUCTURE OF THE LKB1 AND 14-3-3 COMPLEX
Descriptor:14-3-3 protein zeta/delta, Serine/threonine-protein kinase STK11
Authors:Ding, S., Shi, Z.B.
Deposit date:2017-01-08
Release date:2017-04-19
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structure of the complex of phosphorylated liver kinase B1 and 14-3-3 zeta
Acta Crystallogr F Struct Biol Commun, 73, 2017
6ISU
  • Download 6isu
  • View 6isu
Molmil generated image of 6isu
CRYSTAL STRUCTURE OF LYS27-LINKED DI-UBIQUITIN IN COMPLEX WITH ITS SELECTIVE INTERACTING PROTEIN UCHL3
Descriptor:Ubiquitin carboxyl-terminal hydrolase isozyme L3, Ubiquitin
Authors:Ding, S., Pan, M., Zheng, Q., Ren, Y., Hong, D.
Deposit date:2018-11-19
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.866 Å)
Cite:Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains.
Angew. Chem. Int. Ed. Engl., 58, 2019
2LZK
  • Download 2lzk
  • View 2lzk
Molmil generated image of 2lzk
NMR SOLUTION STRUCTURE OF AN N2-GUANINE DNA ADDUCT DERIVED FROM THE POTENT TUMORIGEN DIBENZO[A,L]PYRENE: INTERCALATION FROM THE MINOR GROOVE WITH RUPTURED WATSON-CRICK BASE PAIRING
Descriptor:DNA (5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'), (11S,12S,13S)-11,12,13,14-tetrahydronaphtho[1,2,3,4-pqr]tetraphene-11,12,13-triol
Authors:Tang, Y., Liu, Z., Ding, S., Lin, C.H., Cai, Y., Rodriguez, F.A., Sayer, J.M., Jerina, D.M., Amin, S., Broyde, S., Geacintov, N.E.
Deposit date:2012-10-04
Release date:2012-11-21
Last modified:2013-02-20
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Solution Structure of an N(2)-Guanine DNA Adduct Derived from the Potent Tumorigen Dibenzo[a,l]pyrene: Intercalation from the Minor Groove with Ruptured Watson-Crick Base Pairing.
Biochemistry, 51, 2012
2MIV
  • Download 2miv
  • View 2miv
Molmil generated image of 2miv
NMR STUDIES OF N2-GUANINE ADDUCTS DERIVED FROM THE TUMORIGEN DIBENZO[A,L]PYRENE IN DNA: IMPACT OF ADDUCT STEREOCHEMISTRY, SIZE, AND LOCAL DNA STRUCTURE ON SOLUTION CONFORMATIONS
Descriptor:DNA_(5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA_(5'-D(*GP*GP*TP*AP*GP*GP*AP*TP*GP*G)-3'), (11R,12R,13R)-11,12,13,14-tetrahydronaphtho[1,2,3,4-pqr]tetraphene-11,12,13-triol
Authors:Rodriguez, F.A., Liu, Z., Lin, C.H., Ding, S., Cai, Y., Kolbanovskiy, A., Kolbanovskiy, M., Amin, S., Broyde, S., Geacintov, N.E.
Deposit date:2013-12-20
Release date:2014-04-02
Last modified:2014-04-09
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Studies of an N(2)-Guanine Adduct Derived from the Tumorigen Dibenzo[a,l]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution Conformations.
Biochemistry, 53, 2014
2MIW
  • Download 2miw
  • View 2miw
Molmil generated image of 2miw
NUCLEAR MAGNETIC RESONANCE STUDIES OF N2-GUANINE ADDUCTS DERIVED FROM THE TUMORIGEN DIBENZO[A,L]PYRENE IN DNA: IMPACT OF ADDUCT STEREOCHEMISTRY, SIZE, AND LOCAL DNA STRUCTURE ON SOLUTION CONFORMATIONS
Descriptor:DNA_(5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA_(5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'), (11R,12R,13R)-11,12,13,14-tetrahydronaphtho[1,2,3,4-pqr]tetraphene-11,12,13-triol
Authors:Rodriguez, F.A., Liu, Z., Lin, C.H., Ding, S., Cai, Y., Kolbanovskiy, A., Kolbanovskiy, M., Amin, S., Broyde, S., Geacintov, N.E.
Deposit date:2013-12-20
Release date:2014-04-02
Last modified:2014-04-09
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Studies of an N(2)-Guanine Adduct Derived from the Tumorigen Dibenzo[a,l]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution Conformations.
Biochemistry, 53, 2014
1D8G
  • Download 1d8g
  • View 1d8g
Molmil generated image of 1d8g
ULTRAHIGH RESOLUTION CRYSTAL STRUCTURE OF B-DNA DECAMER D(CCAGTACTGG)
Descriptor:5'-D(*CP*CP*AP*GP*TP*AP*CP*TP*GP*GP*)-3', CALCIUM ION
Authors:Kielkopf, C.L., Ding, S., Kuhn, P., Rees, D.C.
Deposit date:1999-10-23
Release date:2000-02-21
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (0.74 Å)
Cite:Conformational flexibility of B-DNA at 0.74 A resolution: d(CCAGTACTGG)(2).
J.Mol.Biol., 296, 2000
6IIL
  • Download 6iil
  • View 6iil
Molmil generated image of 6iil
USP14 CATALYTIC DOMAIN BIND TO IU1-47
Descriptor:Ubiquitin carboxyl-terminal hydrolase 14, 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(piperidin-1-yl)ethan-1-one
Authors:Mei, Z.Q., Wang, Y.W., Wang, F., Wang, J.W., He, W., Ding, S., Li, J.W.
Deposit date:2018-10-07
Release date:2018-12-12
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018
5KJR
  • Download 5kjr
  • View 5kjr
Molmil generated image of 5kjr
CRYSTAL STRUCTURE OF THE ADCC-POTENT ANTIBODY N60-I3 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120 W69A/S115W MUTANT AND M48U1.
Descriptor:clade A/E 93TH057 HIV-1 gp120 core, M48U1 CD4 MIMETIC PEPTIDE, N60-I3 FAB HEAVY CHAIN, ...
Authors:Tolbert, W.D., Pazgier, M.
Deposit date:2016-06-20
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability.
J.Virol., 90, 2016
5DRZ
  • Download 5drz
  • View 5drz
Molmil generated image of 5drz
CRYSTAL STRUCTURE OF ANTI-HIV-1 ANTIBODY F240 FAB IN COMPLEX WITH GP41 PEPTIDE
Descriptor:HIV Antibody F240 Light Chain, HIV Antibody F240 Heavy Chain, Envelope glycoprotein gp160, ...
Authors:Gohain, N., Tolbert, W.D., Pazgier, M.
Deposit date:2015-09-16
Release date:2016-10-19
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240.
Sci Rep, 6, 2016
5W4L
  • Download 5w4l
  • View 5w4l
Molmil generated image of 5w4l
CRYSTAL STRUCTURE OF THE NON-NEUTRALIZING AND ADCC-POTENT C11-LIKE ANTIBODY N12-I3 IN COMPLEX WITH HIV-1 CLADE A/E GP120, THE CD4 MIMETIC M48U1, AND THE ANTIBODY N5-I5.
Descriptor:clade A/E 93TH057 HIV-1 gp120 core, CD4 mimetic peptide M48U1, Antibody N5-i5 Fab heavy chain, ...
Authors:Tolbert, W.D., Gohain, N., Pazgier, M.
Deposit date:2017-06-12
Release date:2017-11-15
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region.
Structure, 25, 2017
6IIK
  • Download 6iik
  • View 6iik
Molmil generated image of 6iik
USP14 CATALYTIC DOMAIN WITH IU1
Descriptor:Ubiquitin carboxyl-terminal hydrolase 14, 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(pyrrolidin-1-yl)ethan-1-one
Authors:Mei, Z.Q., Wang, Y.W., He, W., Wang, F.
Deposit date:2018-10-06
Release date:2018-12-12
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018
6IIM
  • Download 6iim
  • View 6iim
Molmil generated image of 6iim
USP14 CATALYTIC DOMAIN WITH IU1-206
Descriptor:Ubiquitin carboxyl-terminal hydrolase 14, 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(4-hydroxypiperidin-1-yl)ethan-1-one
Authors:Mei, Z.Q., Wang, J.W., Wang, F., Wang, Y.W.
Deposit date:2018-10-07
Release date:2018-12-12
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018
6IIN
  • Download 6iin
  • View 6iin
Molmil generated image of 6iin
USP14 CATALYTIC DOMAIN WITH IU1-248
Descriptor:Ubiquitin carboxyl-terminal hydrolase 14, 4-{3-[(4-hydroxypiperidin-1-yl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl}benzonitrile
Authors:Mei, Z.Q., Wang, J.W., Wang, F., Wang, Y.W.
Deposit date:2018-10-07
Release date:2018-12-19
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018