2MIV

NMR studies of N2-guanine adducts derived from the tumorigen dibenzo[a,l]pyrene in DNA: Impact of adduct stereochemistry, size, and local DNA structure on solution conformations

Summary for 2MIV

• Entry DOI: 10.2210/pdb2miv/pdb
• Related: 2MIW
• NMR Information: BMRB: 19695
• Descriptor: DNA_(5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA_(5'-D(*GP*GP*TP*AP*GP*GP*AP*TP*GP*G)-3'), (11R,12R,13R)-11,12,13,14-tetrahydronaphtho[1,2,3,4-pqr]tetraphene-11,12,13-triol (3 entities in total)
• Functional Keywords: dna, 14s(-)-trans-anti-db[a, l]p-n2-dg, dna adduct
• Total number of polymer chains: 2
• Total formula weight: 6773.61

Authors

Rodriguez, F.A.,Liu, Z.,Lin, C.H.,Ding, S.,Cai, Y.,Kolbanovskiy, A.,Kolbanovskiy, M.,Amin, S.,Broyde, S.,Geacintov, N.E. (deposition date: 2013-12-20, release date: 2014-04-02, Last modification date: 2014-04-09)

• Primary citation: Rodriguez, F.A.,Liu, Z.,Lin, C.H.,Ding, S.,Cai, Y.,Kolbanovskiy, A.,Kolbanovskiy, M.,Amin, S.,Broyde, S.,Geacintov, N.E.; Nuclear Magnetic Resonance Studies of an N(2)-Guanine Adduct Derived from the Tumorigen Dibenzo[a,l]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution Conformations.; Biochemistry, 53:1827-1841, 2014; PubMed: 24617538; DOI: 10.1021/bi4017044

Experimental method

SOLUTION NMR