8OR4

Partially dissociated CAND1-CUL1-RBX1-SKP1-SKP2-CKS1-CDK2

Summary for 8OR4

Entry DOI	10.2210/pdb8or4/pdb
Related	8OR0 8OR2 8OR3
EMDB information	17117
Descriptor	Cullin-1, E3 ubiquitin-protein ligase RBX1, Cullin-associated NEDD8-dissociated protein 1, ... (7 entities in total)
Functional Keywords	cand1, substrate receptor exchange factor, cullin-ring ligase, crl, scf, ligase, neddylation, dcnl1 co-e3, ubiquitin signaling
Biological source	Homo sapiens (human) More
Total number of polymer chains	7
Total formula weight	353264.75
Authors	Shaaban, M.,Clapperton, J.A.,Ding, S.,Maeots, M.E.,Enchev, R.I. (deposition date: 2023-04-13, release date: 2023-06-28, Last modification date: 2023-07-19)
Primary citation	Shaaban, M.,Clapperton, J.A.,Ding, S.,Kunzelmann, S.,Maeots, M.E.,Maslen, S.L.,Skehel, J.M.,Enchev, R.I. Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange. Mol.Cell, 83:2332-, 2023 Cited by PubMed: 37339624 DOI: 10.1016/j.molcel.2023.05.034 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation