6ONH

Crystal structure of HIV-1 LM/HT Clade A/E CRF01 gp120 core in complex with (S)-MCG-IV-031-A05.

Summary for 6ONH

Entry DOI	10.2210/pdb6onh/pdb
Descriptor	HIV-1 LM/HT Clade A/E CRF01 gp120, 2-acetamido-2-deoxy-beta-D-glucopyranose, (3S)-N~3~-(4-chloro-3-fluorophenyl)-N~1~-propylpiperidine-1,3-dicarboxamide, ... (5 entities in total)
Functional Keywords	hiv-1 gp120, clade a/e cf01, viral protein, viral protein-inhibitor complex, viral protein/inhibitor
Biological source	Human immunodeficiency virus 1
Total number of polymer chains	1
Total formula weight	42258.94
Authors	Tolbert, W.D.,Sherburn, R.,Pazgier, M. (deposition date: 2019-04-22, release date: 2019-10-23, Last modification date: 2023-10-11)
Primary citation	Ding, S.,Grenier, M.C.,Tolbert, W.D.,Vezina, D.,Sherburn, R.,Richard, J.,Prevost, J.,Chapleau, J.P.,Gendron-Lepage, G.,Medjahed, H.,Abrams, C.,Sodroski, J.,Pazgier, M.,Smith 3rd, A.B.,Finzi, A. A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity. J.Virol., 93:-, 2019 Cited by PubMed: 31554684 DOI: 10.1128/JVI.01325-19 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.244 Å)

Structure validation