Author results

2GCN
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CRYSTAL STRUCTURE OF THE HUMAN RHOC-GDP COMPLEX
Descriptor:Rho-related GTP-binding protein RhoC, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Dias, S.M.G., Cerione, R.A.
Deposit date:2006-03-14
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray Crystal Structures Reveal Two Activated States for RhoC.
Biochemistry, 46, 2007
2GCO
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CRYSTAL STRUCTURE OF THE HUMAN RHOC-GPPNHP COMPLEX
Descriptor:Rho-related GTP-binding protein RhoC, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Dias, S.M.G., Cerione, R.A.
Deposit date:2006-03-14
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:X-ray Crystal Structures Reveal Two Activated States for RhoC.
Biochemistry, 46, 2007
2GCP
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CRYSTAL STRUCTURE OF THE HUMAN RHOC-GSP COMPLEX
Descriptor:Rho-related GTP-binding protein RhoC, MAGNESIUM ION, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ...
Authors:Dias, S.M.G., Cerione, R.A.
Deposit date:2006-03-14
Release date:2007-03-27
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:X-ray Crystal Structures Reveal Two Activated States for RhoC.
Biochemistry, 46, 2007
2H77
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CRYSTAL STRUCTURE OF HUMAN TR ALPHA BOUND T3 IN MONOCLINIC SPACE GROUP
Descriptor:THRA protein, 3,5,3'TRIIODOTHYRONINE
Authors:Nascimento, A.S., Dias, S.M.G., Nunes, F.M., Aparicio, R., Bleicher, L., Ambrosio, A.L.B., Figueira, A.C.M., Santos, M.A.M., Neto, M.O., Fischer, H., Togashi, H.F.M., Craievich, A.F., Garrat, R.C., Baxter, J.D., Webb, P., Polikarpov, I.
Deposit date:2006-06-01
Release date:2006-07-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
2H79
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CRYSTAL STRUCTURE OF HUMAN TR ALPHA BOUND T3 IN ORTHORHOMBIC SPACE GROUP
Descriptor:THRA protein, 3,5,3'TRIIODOTHYRONINE
Authors:Nascimento, A.S., Dias, S.M.G., Nunes, F.M., Aparicio, R., Bleicher, L., Ambrosio, A.L.B., Figueira, A.C.M., Santos, M.A.M., Neto, M.O., Fischer, H., Togashi, H.F.M., Craievich, A.F., Garrat, R.C., Baxter, J.D., Webb, P., Polikarpov, I.
Deposit date:2006-06-01
Release date:2006-07-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
3GWS
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CRYSTAL STRUCTURE OF T3-BOUND THYROID HORMONE RECEPTOR
Descriptor:Thyroid hormone receptor beta, 3,5,3'TRIIODOTHYRONINE
Authors:Nascimento, A.S., Dias, S.M.G., Nunes, F.M., Aparicio, R., Polikarpov, I., Baxter, J.D., Webb, P.
Deposit date:2009-04-01
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function
J.Mol.Biol., 360, 2006
4BQM
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CRYSTAL STRUCTURE OF HUMAN LIVER-TYPE GLUTAMINASE, CATALYTIC DOMAIN
Descriptor:GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL, 1,2-ETHANEDIOL, ...
Authors:Ferreira, I.M., Vollmar, M., Krojer, T., Strain-Damerell, C., Froese, S., Coutandin, D., Williams, E., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Dias, S.M.G., Ambrosio, A.L.B., Yue, W.W.
Deposit date:2013-05-31
Release date:2013-07-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain
To be Published
5U0I
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C-TERMINAL ANKYRIN REPEATS FROM HUMAN KIDNEY-TYPE GLUTAMINASE (KGA) - TETRAGONAL CRYSTAL FORM
Descriptor:Glutaminase kidney isoform, mitochondrial, CHLORIDE ION, ...
Authors:Pasquali, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2016-11-24
Release date:2017-05-24
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.423 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5U0J
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C-TERMINAL ANKYRIN REPEATS FROM HUMAN KIDNEY-TYPE GLUTAMINASE (KGA) - MONOCLINIC CRYSTAL FORM
Descriptor:Glutaminase kidney isoform, mitochondrial, SODIUM ION
Authors:Pasquali, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2016-11-24
Release date:2017-05-24
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5U0K
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C-TERMINAL ANKYRIN REPEATS FROM HUMAN LIVER-TYPE GLUTAMINASE (GAB/LGA)
Descriptor:Glutaminase liver isoform, mitochondrial
Authors:Ferreira, I.M., Pasquali, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2016-11-24
Release date:2017-05-24
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.548 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5UQE
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MULTIDOMAIN STRUCTURE OF HUMAN KIDNEY-TYPE GLUTAMINASE(KGA/GLS)
Descriptor:Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
Authors:Pasquali, C.C., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2017-02-08
Release date:2017-05-24
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
3FEX
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CRYSTAL STRUCTURE OF THE CBC-IMPORTIN ALPHA COMPLEX.
Descriptor:Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, Importin subunit alpha-2
Authors:Dias, S.M.G., Ambrosio, A.L.B., Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.549 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
3FEY
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CRYSTAL STRUCTURE OF THE CBC-IMPORTIN ALPHA COMPLEX.
Descriptor:Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, Importin subunit alpha-2
Authors:Dias, S.M.G., Ambrosio, A.L.B., Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
4WN5
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CRYSTAL STRUCTURE OF THE C-TERMINAL PER-ARNT-SIM (PASB) OF HUMAN HIF-3ALPHA9 BOUND TO 18:1-1-MONOACYLGLYCEROL
Descriptor:Hypoxia-inducible factor 3-alpha, SULFATE ION, MONOVACCENIN, ...
Authors:Fala, A.M., Oliveira, J.F., Dias, S.M., Ambrosio, A.L.
Deposit date:2014-10-10
Release date:2015-08-05
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3alpha
Sci.Rep., 5, 2015
4JKT
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, BPTES-BOUND FORM
Descriptor:Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
Authors:Fornezari, C., Ferreira, A.P.S., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2013-03-11
Release date:2013-08-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor.
J.Biol.Chem., 288, 2013
2PTW
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH SULPHATE, IDENTIFICATION OF A METAL BINDING SITE IV
Descriptor:Enolase, ZINC ION, SULFATE ION, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTX
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH SULPHATE IN CLOSED CONFORMATION
Descriptor:Enolase, ZINC ION, SULFATE ION, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTY
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH PEP
Descriptor:Enolase, ZINC ION, PHOSPHOENOLPYRUVATE, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTZ
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH PHOSPHONOACETOHYDROXAMATE (PAH), HIS156-OUT CONFORMATION
Descriptor:Enolase, ZINC ION, PHOSPHONOACETOHYDROXAMIC ACID, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PU0
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH PHOSPHONOACETOHYDROXAMATE (PAH), HIS156-IN CONFORMATION
Descriptor:Enolase, ZINC ION, PHOSPHONOACETOHYDROXAMIC ACID, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PU1
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH FLUORO-PHOSPHONOACETOHYDROXAMATE (FPAH)
Descriptor:Enolase, ZINC ION, [(1S)-1-FLUORO-2-(HYDROXYAMINO)-2-OXOETHYL]PHOSPHONIC ACID, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
3JZB
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CRYSTAL STRUCTURE OF TR-ALFA BOUND TO THE SELECTIVE THYROMIMETIC TRIAC
Descriptor:THRA protein, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
Authors:Nascimento, A.S., Dias, S.M.G., Nunes, F.M., Aparicio, R.
Deposit date:2009-09-23
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:Gaining ligand selectivity in thyroid hormone receptors via entropy.
Proc.Natl.Acad.Sci.USA, 106, 2009
3SS3
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, LIGAND-FREE FORM
Descriptor:Glutaminase C, CHLORIDE ION
Authors:Ambrosio, A.L.B., Dias, S.M.G., Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SS4
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, PHOSPHATE-BOUND FORM
Descriptor:Glutaminase C, PHOSPHATE ION
Authors:Ambrosio, A.L.B., Dias, S.M.G., Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SS5
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, L-GLUTAMATE-BOUND FORM
Descriptor:Glutaminase C, GLUTAMIC ACID
Authors:Ambrosio, A.L.B., Dias, S.M.G., Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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