1JMS | | CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF MURINE TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE | | Descriptor: | TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE, MAGNESIUM ION, SODIUM ION | | Authors: | Delarue, M., Boule, J.B., Lescar, J., Expert-Bezancon, N., Sukumar, N., Jourdan, N., Rougeon, F., Papanicolaou, C. | | Deposit date: | 2001-07-19 | | Release date: | 2002-01-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase.
Embo J., 21, 2002
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2J0E | | THREE DIMENSIONAL STRUCTURE AND CATALYTIC MECHANISM OF 6- PHOSPHOGLUCONOLACTONASE FROM TRYPANOSOMA BRUCEI | | Descriptor: | 6-PHOSPHOGLUCONOLACTONASE, ZINC ION, MERCURY (II) ION, ... | | Authors: | Delarue, M., Duclert-Savatier, N., Miclet, E., Haouz, A., Giganti, D., Ouazzani, J., Lopez, P., Nilges, M., Stoven, V. | | Deposit date: | 2006-08-02 | | Release date: | 2007-01-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Three Dimensional Structure and Implications for the Catalytic Mechanism of 6-Phosphogluconolactonase from Trypanosoma Brucei.
J.Mol.Biol., 366, 2007
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1KDH | | BINARY COMPLEX OF MURINE TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE WITH A PRIMER SINGLE STRANDED DNA | | Descriptor: | 5'-D(P*(BRU)P*(BRU)P*(BRU)P*(BRU))-3', Terminal deoxynucleotidyltransferase short isoform, MAGNESIUM ION, ... | | Authors: | Delarue, M., Boule, J.B., Lescar, J., Expert-Bezancon, N., Jourdan, N., Sukumar, N., Rougeon, F., Papanicolaou, C. | | Deposit date: | 2001-11-13 | | Release date: | 2002-05-13 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase.
EMBO J., 21, 2002
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1KEJ | | CRYSTAL STRUCTURE OF MURINE TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE COMPLEXED WITH DDATP | | Descriptor: | Terminal deoxynucleotidyltransferase short isoform, COBALT (II) ION, SODIUM ION, ... | | Authors: | Delarue, M., Boule, J.B., Lescar, J., Expert-Bezancon, N., Jourdan, N., Sukumar, N., Rougeon, F., Papanicolaou, C. | | Deposit date: | 2001-11-16 | | Release date: | 2002-05-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase.
EMBO J., 21, 2002
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6V4A | |
6V4B | | DECLIC N-TERMINAL DOMAIN 34-202 | | Descriptor: | Neur_chan_LBD domain-containing protein, GLYCEROL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Delarue, M., Hu, H.D. | | Deposit date: | 2019-11-27 | | Release date: | 2020-06-03 | | Last modified: | 2020-07-01 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6V4S | |
1ATT | |
1N5I | | CRYSTAL STRUCTURE OF INACTIVE MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE MONOPHOSPHATE (TMP) AT PH 4.6 (RESOLUTION 1.85 A) | | Descriptor: | THYMIDYLATE KINASE, SULFATE ION, CITRATE ANION, ... | | Authors: | Fioravanti, E., Haouz, A., Ursby, T., Munier-Lehmann, H., Delarue, M., Bourgeois, D. | | Deposit date: | 2002-11-06 | | Release date: | 2003-04-08 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Mycobacterium tuberculosis Thymidylate Kinase: Structural Studies of Intermediates along the Reaction Pathway
J.Mol.Biol., 327, 2003
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1N5J | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE DIPHOSPHATE (TDP) AND THYMIDINE TRIPHOSPHATE (TTP) AT PH 5.4 (1.85 A RESOLUTION) | | Descriptor: | THYMIDYLATE KINASE, SULFATE ION, MAGNESIUM ION, ... | | Authors: | Fioravanti, E., Haouz, A., Ursby, T., Munier-Lehmann, H., Delarue, M., Bourgeois, D. | | Deposit date: | 2002-11-06 | | Release date: | 2003-04-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Mycobacterium tuberculosis Thymidylate Kinase: Structural Studies of Intermediates along the
Reaction Pathway
J.Mol.Biol., 327, 2003
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1N5K | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE CRYSTALLIZED IN SODIUM MALONATE (RESOLUTION 2.1 A) | | Descriptor: | THYMIDYLATE KINASE, ACETATE ION, THYMIDINE-5'-PHOSPHATE, ... | | Authors: | Fioravanti, E., Haouz, A., Ursby, T., Munier-Lehmann, H., Delarue, M., Bourgeois, D. | | Deposit date: | 2002-11-06 | | Release date: | 2003-04-15 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mycobacterium tuberculosis Thymidylate Kinase: Structural Studies of Intermediates along the
Reaction Pathway
J.Mol.Biol., 375, 2003
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1N5L | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE CRYSTALLIZED IN SODIUM MALONATE, AFTER CATALYSIS IN THE CRYSTAL (2.3 A RESOLUTION) | | Descriptor: | THYMIDYLATE KINASE, ACETATE ION, THYMIDINE-5'-PHOSPHATE, ... | | Authors: | Fioravanti, E., Haouz, A., Ursby, T., Munier-Lehmann, H., Delarue, M., Bourgeois, D. | | Deposit date: | 2002-11-06 | | Release date: | 2003-04-15 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Mycobacterium tuberculosis Thymidylate Kinase: Structural Studies of Intermediates along the
Reaction Pathway
J.Mol.Biol., 375, 2003
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1GSI | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE MONOPHOSPHATE (TMP) | | Descriptor: | THYMIDYLATE KINASE, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, ... | | Authors: | Ursby, T., Weik, M., Fioravanti, E., Delarue, M., Goeldner, M., Bourgeois, D. | | Deposit date: | 2002-01-03 | | Release date: | 2002-03-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cryophotolysis of Caged Compounds: A Technique for Trapping Intermediate States in Protein Crystals
Acta Crystallogr.,Sect.D, 58, 2002
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1GTV | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE-5'-DIPHOSPHATE (TDP) | | Descriptor: | THYMIDYLATE KINASE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ... | | Authors: | Ursby, T., Weik, M., Fioravanti, E., Delarue, M., Goeldner, M., Bourgeois, D. | | Deposit date: | 2002-01-21 | | Release date: | 2002-03-28 | | Last modified: | 2018-11-21 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Cryophotolysis of Caged Compounds: A Technique for Trapping Intermediate States in Protein Crystals
Acta Crystallogr.,Sect.D, 58, 2002
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5L47 | | X-RAY STRUCTURE OF THE 2-22' LOCALLY-CLOSED MUTANT OF GLIC IN COMPLEX WITH CYANOSELENOBARBITAL (SELENIATED BARBITURATE) | | Descriptor: | Proton-gated ion channel, CHLORIDE ION, ACETATE ION, ... | | Authors: | Reinholds Ruza, R., Fourati, Z., Delarue, M. | | Deposit date: | 2016-05-25 | | Release date: | 2016-12-21 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State.
J. Biol. Chem., 292, 2017
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5L4E | | X-RAY STRUCTURE OF THE 2-22' LOCALLY-CLOSED MUTANT OF GLIC IN COMPLEX WITH THIOPENTAL | | Descriptor: | Proton-gated ion channel, DODECANE, CHLORIDE ION, ... | | Authors: | Fourati, Z., Ruza, R.R., Delarue, M. | | Deposit date: | 2016-05-25 | | Release date: | 2016-12-21 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State.
J. Biol. Chem., 292, 2017
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5L4H | | X-RAY STRUCTURE OF THE 2-22' LOCALLY-CLOSED MUTANT OF GLIC IN COMPLEX WITH 5-(2-BROMO-ETHYL)-5-ETHYL-PYRIMIDINE-2,4,6-TRIONE (BROMINATED BARBITURATE) | | Descriptor: | Proton-gated ion channel, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Fourati, Z., Ruza, R.R., Delarue, M. | | Deposit date: | 2016-05-25 | | Release date: | 2016-12-21 | | Last modified: | 2017-02-15 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State.
J. Biol. Chem., 292, 2017
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1G3U | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE MONOPHOSPHATE (TMP) | | Descriptor: | THYMIDYLATE KINASE, SULFATE ION, MAGNESIUM ION, ... | | Authors: | Li de la Sierra, I., Munier-Lehmann, H., Gilles, A.M., Barzu, O., Delarue, M. | | Deposit date: | 2000-10-25 | | Release date: | 2001-10-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 A resolution.
J.Mol.Biol., 311, 2001
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1EQR | | CRYSTAL STRUCTURE OF FREE ASPARTYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI | | Descriptor: | ASPARTYL-TRNA SYNTHETASE, MAGNESIUM ION | | Authors: | Rees, B., Webster, G., Delarue, M., Boeglin, M., Moras, D. | | Deposit date: | 2000-04-06 | | Release date: | 2000-06-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Aspartyl tRNA-synthetase from Escherichia coli: flexibility and adaptability to the substrates.
J.Mol.Biol., 299, 2000
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1MRN | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH BISUBSTRATE INHIBITOR (TP5A) | | Descriptor: | Thymidylate Kinase, SULFATE ION, MAGNESIUM ION, ... | | Authors: | Haouz, A., Vanheusden, V., Munier-Lehmann, H., Froeyen, M., Herdewijn, P., Van Calenbergh, S., Delarue, M. | | Deposit date: | 2002-09-18 | | Release date: | 2003-01-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.
J.Biol.Chem., 278, 2003
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3EAM | | AN OPEN-PORE STRUCTURE OF A BACTERIAL PENTAMERIC LIGAND-GATED ION CHANNEL | | Descriptor: | Glr4197 protein, DODECYL-BETA-D-MALTOSIDE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | | Authors: | Bocquet, N., Nury, H., Baaden, M., Le Poupon, C., Changeux, J.P., Delarue, M., Corringer, P.J. | | Deposit date: | 2008-08-26 | | Release date: | 2008-11-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation.
Nature, 457, 2009
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3FHJ | | INDEPENDENT SATURATION OF THREE TRPRS SUBSITES GENERATES A PARTIALLY-ASSEMBLED STATE SIMILAR TO THOSE OBSERVED IN MOLECULAR SIMULATIONS | | Descriptor: | Tryptophanyl-tRNA synthetase, TRYPTOPHAN, PHOSPHATE ION, ... | | Authors: | Laowanapiban, P., Kapustina, M., Vonrhein, C., Delarue, M., Koehl, P., Carter Jr., C.W. | | Deposit date: | 2008-12-09 | | Release date: | 2009-02-03 | | Last modified: | 2020-01-22 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations.
Proc.Natl.Acad.Sci.Usa, 106, 2009
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3FI0 | | CRYSTAL STRUCTURE ANALYSIS OF B. STEAROTHERMOPHILUS TRYPTOPHANYL-TRNA SYNTHETASE COMPLEXED WITH TRYPTOPHAN, AMP, AND INORGANIC PHOSPHATE | | Descriptor: | Tryptophanyl-tRNA synthetase, TRYPTOPHAN, PHOSPHATE ION, ... | | Authors: | Laowanapiban, P., Kapustina, M., Vonrhein, C., Delarue, M., Koehl, P., Carter Jr., C.W. | | Deposit date: | 2008-12-10 | | Release date: | 2009-02-03 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations.
Proc.Natl.Acad.Sci.Usa, 106, 2009
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3P4W | | STRUCTURE OF DESFLURANE BOUND TO A PENTAMERIC LIGAND-GATED ION CHANNEL, GLIC | | Descriptor: | Glr4197 protein, DODECYL-BETA-D-MALTOSIDE, (2S)-2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane, ... | | Authors: | Nury, H., Van Renterghem, C., Weng, Y., Tran, A., Baaden, M., Dufresne, V., Changeux, J.P., Sonner, J.M., Delarue, M., Corringer, P.J. | | Deposit date: | 2010-10-07 | | Release date: | 2011-01-19 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
Nature, 469, 2011
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3P50 | | STRUCTURE OF PROPOFOL BOUND TO A PENTAMERIC LIGAND-GATED ION CHANNEL, GLIC | | Descriptor: | Glr4197 protein, DODECYL-BETA-D-MALTOSIDE, 2,6-BIS(1-METHYLETHYL)PHENOL, ... | | Authors: | Nury, H., Van Renterghem, C., Weng, Y., Tran, A., Baaden, M., Dufresne, V., Changeux, J.P., Sonner, J.M., Delarue, M., Corringer, P.J. | | Deposit date: | 2010-10-07 | | Release date: | 2011-01-19 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
Nature, 469, 2011
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