1N5L

CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE CRYSTALLIZED IN SODIUM MALONATE, AFTER CATALYSIS IN THE CRYSTAL (2.3 A RESOLUTION)

Summary for 1N5L

Entry DOI	10.2210/pdb1n5l/pdb
Related	1GTV 1N5I 1N5J 1N5K
Descriptor	THYMIDYLATE KINASE, ACETATE ION, THYMIDINE-5'-PHOSPHATE, ... (7 entities in total)
Functional Keywords	transferase (atp:tmp phosphotransferase), kinase, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	46365.78
Authors	Fioravanti, E.,Haouz, A.,Ursby, T.,Munier-Lehmann, H.,Delarue, M.,Bourgeois, D. (deposition date: 2002-11-06, release date: 2003-04-15, Last modification date: 2024-02-14)
Primary citation	Fioravanti, E.,Haouz, A.,Ursby, T.,Munier-Lehmann, H.,Delarue, M.,Bourgeois, D. Mycobacterium tuberculosis Thymidylate Kinase: Structural Studies of Intermediates along the Reaction Pathway J.Mol.Biol., 375:1077-1092, 2003 Cited by PubMed: 12662932 DOI: 10.1016/S0022-2836(03)00202-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation