6V4A

An open conformation of a Pentameic ligand-gated ion channel with additional N-terminal domain

Summary for 6V4A

Entry DOI	10.2210/pdb6v4a/pdb
Descriptor	Neur_chan_LBD domain-containing protein, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL (3 entities in total)
Functional Keywords	pentameric ligand-gated ion channel, transport protein
Biological source	uncultured Desulfofustis sp. PB-SRB1
Total number of polymer chains	5
Total formula weight	363645.66
Authors	Delarue, M.,Hu, H.D. (deposition date: 2019-11-27, release date: 2020-06-03, Last modification date: 2023-10-11)
Primary citation	Hu, H.,Howard, R.J.,Bastolla, U.,Lindahl, E.,Delarue, M. Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel. Proc.Natl.Acad.Sci.USA, 117:13437-13446, 2020 Cited by PubMed: 32482881 DOI: 10.1073/pnas.1922701117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.83 Å)

Structure validation