6V4A

An open conformation of a Pentameic ligand-gated ion channel with additional N-terminal domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0007165	biological_process	signal transduction
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042391	biological_process	regulation of membrane potential
A	0043005	cellular_component	neuron projection
A	0046872	molecular_function	metal ion binding
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0007165	biological_process	signal transduction
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042391	biological_process	regulation of membrane potential
B	0043005	cellular_component	neuron projection
B	0046872	molecular_function	metal ion binding
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0007165	biological_process	signal transduction
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042391	biological_process	regulation of membrane potential
C	0043005	cellular_component	neuron projection
C	0046872	molecular_function	metal ion binding
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0007165	biological_process	signal transduction
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042391	biological_process	regulation of membrane potential
D	0043005	cellular_component	neuron projection
D	0046872	molecular_function	metal ion binding
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0007165	biological_process	signal transduction
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042391	biological_process	regulation of membrane potential
E	0043005	cellular_component	neuron projection
E	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue TRS A 701

Chain	Residue
A	ASP122
A	ASP123
A	GLY125
A	LYS127
A	GLY128
A	SER130
A	ALA131
A	SER132

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site_id	AC2
Number of Residues	3
Details	binding site for residue P3A A 702

Chain	Residue
B	LEU567
B	ASP577
A	TYR517

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site_id	AC3
Number of Residues	5
Details	binding site for residue P3A A 703

Chain	Residue
A	ASN560
A	GLY565
A	LEU567
A	ARG569
A	ASP577

---

site_id	AC4
Number of Residues	8
Details	binding site for residue TRS E 701

Chain	Residue
E	ASP122
E	ASP123
E	GLY125
E	LYS127
E	GLY128
E	SER130
E	ALA131
E	SER132

---

site_id	AC5
Number of Residues	3
Details	binding site for residue P3A E 702

Chain	Residue
D	TYR517
E	ASN560
E	ASP577

---

site_id	AC6
Number of Residues	5
Details	binding site for residue TRS D 701

Chain	Residue
D	ASP122
D	ASP123
D	GLY128
D	SER130
D	SER132

---

site_id	AC7
Number of Residues	7
Details	binding site for residue TRS C 701

Chain	Residue
C	ASP122
C	ASP123
C	GLY125
C	GLY128
C	SER130
C	ALA131
C	SER132

---

site_id	AC8
Number of Residues	1
Details	binding site for residue P3A C 702

Chain	Residue
C	TYR517

---

site_id	AC9
Number of Residues	7
Details	binding site for residue TRS B 701

Chain	Residue
B	ASP122
B	ASP123
B	GLY128
B	SER130
B	ALA131
B	SER132
C	GLN277

---

site_id	AD1
Number of Residues	5
Details	binding site for residue P3A B 702

Chain	Residue
B	TYR517
B	THR562
C	GLY565
C	LEU567
C	ARG569

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