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1A3Q
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BU of 1a3q by Molmil
HUMAN NF-KAPPA-B P52 BOUND TO DNA
Descriptor: DNA (5'-D(*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*CP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B P52)
Authors:Cramer, P, Larson, C.J, Verdine, G.L, Muller, C.W.
Deposit date:1998-01-23
Release date:1998-06-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
EMBO J., 16, 1997
1I3Q
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BU of 1i3q by Molmil
RNA POLYMERASE II CRYSTAL FORM I AT 3.1 A RESOLUTION
Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ...
Authors:Cramer, P, Bushnell, D.A, Kornberg, R.D.
Deposit date:2001-02-15
Release date:2001-04-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science, 292, 2001
1I50
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BU of 1i50 by Molmil
RNA POLYMERASE II CRYSTAL FORM II AT 2.8 A RESOLUTION
Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ...
Authors:Cramer, P, Bushnell, D.A, Kornberg, R.D.
Deposit date:2001-02-23
Release date:2001-04-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science, 292, 2001
1BVO
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BU of 1bvo by Molmil
DORSAL HOMOLOGUE GAMBIF1 BOUND TO DNA
Descriptor: DNA DUPLEX, TRANSCRIPTION FACTOR GAMBIF1
Authors:Cramer, P, Varrot, A, Barillas-Mury, C, Kafatos, F.C, Mueller, C.W.
Deposit date:1998-09-16
Release date:1999-07-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA.
Structure Fold.Des., 7, 1999
1Y1Y
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BU of 1y1y by Molmil
RNA Polymerase II-TFIIS-DNA/RNA complex
Descriptor: 5'-D(P*TP*AP*CP*GP*CP*CP*T)-3', 5'-R(P*AP*GP*GP*C)-3', DNA-directed RNA polymerase II 13.6 kDa polypeptide, ...
Authors:Cramer, P, Kettenberger, H, Armache, K.-J.
Deposit date:2004-11-19
Release date:2004-12-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.
Mol.Cell, 16, 2004
1Y1W
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BU of 1y1w by Molmil
Complete RNA Polymerase II elongation complex
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
Authors:Cramer, P, Kettenberger, H, Armache, K.-J.
Deposit date:2004-11-19
Release date:2005-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16, 2004
5FYW
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BU of 5fyw by Molmil
Transcription initiation complex structures elucidate DNA opening (OC)
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P.
Deposit date:2016-03-10
Release date:2016-05-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Transcription Initiation Complex Structures Elucidate DNA Opening
Nature, 533, 2016
6I84
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BU of 6i84 by Molmil
Structure of transcribing RNA polymerase II-nucleosome complex
Descriptor: DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Farnung, L, Vos, S.M, Cramer, P.
Deposit date:2018-11-19
Release date:2019-01-02
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of transcribing RNA polymerase II-nucleosome complex.
Nat Commun, 9, 2018
8B3G
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BU of 8b3g by Molmil
C(N)RL4CSA-UVSSA-E2-ubiquitin complex.
Descriptor: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-8, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2022-09-16
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair.
Nat.Struct.Mol.Biol., 31, 2024
6ERP
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BU of 6erp by Molmil
Structure of the human mitochondrial transcription initiation complex at the LSP promoter
Descriptor: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ...
Authors:Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (4.502 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
4V1N
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BU of 4v1n by Molmil
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-08
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
4V1O
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BU of 4v1o by Molmil
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
8CEN
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BU of 8cen by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Schilbach, S, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-22
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
6EXV
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BU of 6exv by Molmil
Structure of mammalian RNA polymerase II elongation complex inhibited by Alpha-amanitin
Descriptor: AMATOXIN, DNA (25-MER), DNA (36-MER), ...
Authors:Liu, X, Farnung, L, Wigge, C, Cramer, P.
Deposit date:2017-11-09
Release date:2018-03-21
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin.
J. Biol. Chem., 293, 2018
8BZ1
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BU of 8bz1 by Molmil
RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8BYQ
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BU of 8byq by Molmil
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
4V1M
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BU of 4v1m by Molmil
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-D(*CP*CP*AP*GP*GP*AP)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*CP *CP*BRUP*GP*GP*TP*C)-3', ...
Authors:Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
4YM7
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BU of 4ym7 by Molmil
RNA polymerase I structure with an alternative dimer hinge
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Kostrewa, D, Kuhn, C.-D, Engel, C, Cramer, P.
Deposit date:2015-03-06
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:An alternative RNA polymerase I structure reveals a dimer hinge.
Acta Crystallogr.,Sect.D, 71, 2015
3LPE
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BU of 3lpe by Molmil
Crystal structure of Spt4/5NGN heterodimer complex from Methanococcus jannaschii
Descriptor: DNA-directed RNA polymerase subunit E'', Putative transcription antitermination protein nusG, ZINC ION
Authors:Hirtreiter, A, Damsma, G.E, Cheung, A.C.M, Klose, D, Grohmann, D, Vojnic, E, Martin, A.C.R, Cramer, P, Werner, F.
Deposit date:2010-02-05
Release date:2010-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif.
Nucleic Acids Res., 38, 2010
3M1M
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BU of 3m1m by Molmil
Crystal structure of the primase-polymerase from Sulfolobus islandicus
Descriptor: GLYCEROL, ORF904, SULFATE ION, ...
Authors:Vannini, A, Beck, K, Lipps, G, Cramer, P.
Deposit date:2010-03-05
Release date:2010-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis
Nucleic Acids Res., 38, 2010
1I6H
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BU of 1i6h by Molmil
RNA POLYMERASE II ELONGATION COMPLEX
Descriptor: 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ...
Authors:Gnatt, A.L, Cramer, P, Kornberg, R.D.
Deposit date:2001-03-02
Release date:2001-04-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
Science, 292, 2001
7NVR
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BU of 7nvr by Molmil
Human Mediator with RNA Polymerase II Pre-initiation complex
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Rengachari, S, Schilbach, S, Aibara, S, Cramer, P.
Deposit date:2021-03-15
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7NVS
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BU of 7nvs by Molmil
RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7NVV
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BU of 7nvv by Molmil
XPB-containing part of TFIIH in a post-translocated state (with ADP-BeF3)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, General transcription and DNA repair factor IIH helicase subunit XPB, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021

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