4V1M

Architecture of the RNA polymerase II-Mediator core transcription initiation complex

Summary for 4V1M

Related4V1N 4V1O
EMDB information2784
DescriptorDNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, ... (15 entities in total)
Functional Keywordstranscription, transcription initiation, rna polymerase ii, general transcription factors
Biological sourceSACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
More
Cellular locationNucleus P04050 P08518 P16370 P20434 P20436 P38902
Cytoplasm  P20435
Nucleus, nucleolus  P27999 P22139 P40422
Total number of polymer chains13
Total molecular weight481286.62
Authors
Plaschka, C.,Lariviere, L.,Wenzeck, L.,Hemann, M.,Tegunov, D.,Petrotchenko, E.V.,Borchers, C.H.,Baumeister, W.,Herzog, F.,Villa, E.,Cramer, P. (deposition date: 2014-09-29, release date: 2015-02-04, Last modification date: 2017-08-02)
Primary citation
Plaschka, C.,Lariviere, L.,Wenzeck, L.,Seizl, M.,Hemann, M.,Tegunov, D.,Petrotchenko, E.V.,Borchers, C.H.,Baumeister, W.,Herzog, F.,Villa, E.,Cramer, P.
Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518:376-, 2015
PubMed: 25652824 (PDB entries with the same primary citation)
DOI: 10.1038/NATURE14229
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (6.6 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone93.5%13.2%0.72MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures