Author results

1KPM
  • Download 1kpm
  • View 1kpm
Molmil generated image of 1kpm
FIRST STRUCTURAL EVIDENCE OF A SPECIFIC INHIBITION OF PHOSPHOLIPASE A2 BY VITAMIN E AND ITS IMPLICATIONS IN INFLAMMATION: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND VITAMIN E AT 1.8 A RESOLUTION.
Descriptor:Phospholipase A2, VITAMIN E, ACETIC ACID
Authors:Chandra, V., Jasti, J., Kaur, P., Betzel, C., Srinivasan, A., Singh, T.P.
Deposit date:2002-01-01
Release date:2002-07-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:First Structural Evidence of a Specific Inhibition of Phospholipase A2 by alpha-Tocopherol (Vitamin E) and its Implications in Inflammation: Crystal Structure of the Complex Formed Between Phospholipase A2 and alpha-Tocopherol at 1.8 A Resolution
J.Mol.Biol., 320, 2002
1JQ9
  • Download 1jq9
  • View 1jq9
Molmil generated image of 1jq9
CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA AND A DESIGNED PENTAPEPTIDE PHE-LEU-SER-TYR-LYS AT 1.8 RESOLUTION
Descriptor:Phospholipase A2, Peptide inhibitor, ACETIC ACID
Authors:Chandra, V., Jasti, J., Kaur, P., Dey, S., Betzel, C., Singh, T.P.
Deposit date:2001-08-04
Release date:2002-11-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A Resolution
J.BIOL.CHEM., 277, 2002
1JQ8
  • Download 1jq8
  • View 1jq8
Molmil generated image of 1jq8
DESIGN OF SPECIFIC INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA AND A DESIGNED PENTAPEPTIDE LEU-ALA-ILE-TYR-SER AT 2.0 RESOLUTION
Descriptor:Phospholipase A2, Peptide inhibitor, SULFATE ION, ...
Authors:Chandra, V., Jasti, J., Kaur, P., Dey, S., Betzel, C., Singh, T.P.
Deposit date:2001-08-04
Release date:2002-11-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS).
ACTA CRYSTALLOGR.,SECT.D, 58, 2002
1FV0
  • Download 1fv0
  • View 1fv0
Molmil generated image of 1fv0
FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID
Descriptor:PHOSPHOLIPASE A2, SULFATE ION, ACETATE ION, ...
Authors:Chandra, V., Jasti, J., Kaur, P., Srinivasan, A., Betzel, C., Singh, T.P.
Deposit date:2000-09-18
Release date:2002-08-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Phospholipase A2 Inhibition for the Synthesis of Prostaglandins by the Plant Alkaloid Aristolochic Acid from a 1.7 A Crystal Structure
Biochemistry, 41, 2002
1CL5
  • Download 1cl5
  • View 1cl5
Molmil generated image of 1cl5
CRYSTAL STRUCTURE OF PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA
Descriptor:PROTEIN (PHOSPHOLIPASE A2)
Authors:Chandra, V., Kaur, P., Singh, T.P.
Deposit date:1999-05-06
Release date:1999-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Three-dimensional structure of a presynaptic neurotoxic phospholipase A2 from Daboia russelli pulchella at 2.4 A resolution.
J.Mol.Biol., 296, 2000
1FB2
  • Download 1fb2
  • View 1fb2
Molmil generated image of 1fb2
STRUCTURE OF PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA AT 1.95
Descriptor:PHOSPHOLIPASE A2
Authors:Chandra, V., Kaur, P., Betzel, C., Singh, T.P.
Deposit date:2000-07-14
Release date:2001-07-25
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Regulation of catalytic function by molecular association: structure of phospholipase A2 from Daboia russelli pulchella (DPLA2) at 1.9 A resolution.
Acta Crystallogr.,Sect.D, 57, 2001
3DZU
  • Download 3dzu
  • View 3dzu
Molmil generated image of 3dzu
INTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH BVT.13, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
Descriptor:Retinoic acid receptor RXR-alpha, Peroxisome proliferator-activated receptor gamma, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ...
Authors:Chandra, V., Huang, P., Hamuro, Y., Raghuram, S., Wang, Y., Burris, T.P., Rastinejad, F.
Deposit date:2008-07-30
Release date:2008-10-28
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
3DZY
  • Download 3dzy
  • View 3dzy
Molmil generated image of 3dzy
INTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH ROSIGLITAZONE, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
Descriptor:Retinoic acid receptor RXR-alpha, Peroxisome proliferator-activated receptor gamma, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ...
Authors:Chandra, V., Huang, P., Hamuro, Y., Raghuram, S., Wang, Y., Burris, T.P., Rastinejad, F.
Deposit date:2008-07-30
Release date:2008-10-28
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
3E00
  • Download 3e00
  • View 3e00
Molmil generated image of 3e00
INTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH GW9662, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
Descriptor:Retinoic acid receptor RXR-alpha, Peroxisome proliferator-activated receptor gamma, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ...
Authors:Chandra, V., Huang, P., Hamuro, Y., Raghuram, S., Wang, Y., Burris, T.P., Rastinejad, F.
Deposit date:2008-07-30
Release date:2008-10-28
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
4IQR
  • Download 4iqr
  • View 4iqr
Molmil generated image of 4iqr
MULTI-DOMAIN ORGANIZATION OF THE HNF4ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA
Descriptor:Hepatocyte nuclear factor 4-alpha, DNA (5'-D(*GP*GP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*C)-3'), ...
Authors:Chandra, V., Huang, P., Kim, Y., Rastinejad, F.
Deposit date:2013-01-13
Release date:2013-03-20
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Multidomain integration in the structure of the HNF-4 alpha nuclear receptor complex.
Nature, 495, 2013
5UAN
  • Download 5uan
  • View 5uan
Molmil generated image of 5uan
CRYSTAL STRUCTURE OF MULTI-DOMAIN RAR-BETA-RXR-ALPHA HETERODIMER ON DNA
Descriptor:Retinoic acid receptor RXR-alpha, Retinoic acid receptor beta, Nuclear receptor coactivator 2, ...
Authors:Chandra, V., Wu, D., Kim, Y., Rastinejad, F.
Deposit date:2016-12-19
Release date:2017-10-18
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.508 Å)
Cite:The quaternary architecture of RAR beta-RXR alpha heterodimer facilitates domain-domain signal transmission.
Nat Commun, 8, 2017
1OXL
  • Download 1oxl
  • View 1oxl
Molmil generated image of 1oxl
INHIBITION OF PHOSPHOLIPASE A2 (PLA2) BY (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)-ACETIC ACID (INDOLE): CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PLA2 FROM RUSSELL'S VIPER AND INDOLE AT 1.8 RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID, CARBONATE ION, ...
Authors:Chandra, V., Balasubramanya, R., Kaur, P., Singh, T.P.
Deposit date:2003-04-02
Release date:2004-04-06
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the complex of the secretory phospholipase A2 from Daboia russelli pulchella with an endogenic indole derivative, 2-carbamoylmethyl-5-propyl-octahydro-indol-7-yl-acetic acid at 1.8 A resolution.
Biochim.Biophys.Acta, 1752, 2005
1P7V
  • Download 1p7v
  • View 1p7v
Molmil generated image of 1p7v
STRUCTURE OF A COMPLEX FORMED BETWEEN PROTEINASE K AND A DESIGNED HEPTAPEPTIDE INHIBITOR PRO-ALA-PRO-PHE-ALA-ALA-ALA AT ATOMIC RESOLUTION
Descriptor:proteinase K, inhibitor peptide, CALCIUM ION, ...
Authors:Bilgrami, S., Kaur, P., Chandra, V., Banumathi, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2003-05-06
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Structure of a complex formed between Proteinase K and a designed heptapeptide inhibitor Pro-Ala-Pro-Phe-Ala-Ala-Ala at atomic resolution
To be published
1P7W
  • Download 1p7w
  • View 1p7w
Molmil generated image of 1p7w
CRYSTAL STRUCTURE OF THE COMPLEX OF PROTEINASE K WITH A DESIGNED HEPTAPEPTIDE INHIBITOR PRO-ALA-PRO-PHE-ALA-SER-ALA AT ATOMIC RESOLUTION
Descriptor:proteinase K, inhibitor peptide, CALCIUM ION, ...
Authors:Bilgrami, S., Perbandt, M., Chandra, V., Banumathi, S., Kaur, P., Betzel, C., Singh, T.P.
Deposit date:2003-05-06
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Crystal structure of the complex of Proteinase K with heptapeptide inhibitor Pro-Ala-Pro-Phe-Ala-Ser-Ala at atomic resolution
To be published
3M9Q
  • Download 3m9q
  • View 3m9q
Molmil generated image of 3m9q
DROSOPHILA MSL3 CHROMODOMAIN
Descriptor:Protein male-specific lethal-3
Authors:Kim, D., Huang, P., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2010-03-22
Release date:2010-07-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain.
Nat.Struct.Mol.Biol., 17, 2010
3OA6
  • Download 3oa6
  • View 3oa6
Molmil generated image of 3oa6
HUMAN MSL3 CHROMODOMAIN BOUND TO DNA AND H4K20ME1 PEPTIDE
Descriptor:Male-specific lethal 3 homolog, DNA (5'-D(*GP*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*AP*G)-3'), ...
Authors:Kim, D., Huang, P., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2010-08-04
Release date:2010-08-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain.
Nat.Struct.Mol.Biol., 17, 2010
6Q38
  • Download 6q38
  • View 6q38
Molmil generated image of 6q38
THE CRYSTAL STRUCTURE OF CK2A BOUND TO P1-C4
Descriptor:Casein kinase II subunit alpha, Stapled Peptide, BENZOIC ACID
Authors:Brear, P., Iegre, J., Baker, D., Tan, Y., Sore, H., Donovan, D., Spring, D., Chandra, V., Hyvonen, M.
Deposit date:2018-12-03
Release date:2019-04-24
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Efficient development of stable and highly functionalised peptides targeting the CK2 alpha /CK2 beta protein-protein interaction.
Chem Sci, 10, 2019
6Q4Q
  • Download 6q4q
  • View 6q4q
Molmil generated image of 6q4q
THE CRYSTAL STRUCTURE OF CK2A BOUND TO P2-C4
Descriptor:Casein kinase II subunit alpha, Stapled peptide, GLYCEROL, ...
Authors:Brear, P., Iegre, J., Baker, D., Tan, Y., Sore, H., Donovan, D., Spring, D., Chandra, V., Hyvonen, M.
Deposit date:2018-12-06
Release date:2019-04-24
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Efficient development of stable and highly functionalised peptides targeting the CK2 alpha /CK2 beta protein-protein interaction.
Chem Sci, 10, 2019
5VET
  • Download 5vet
  • View 5vet
Molmil generated image of 5vet
PHOSPHOLIPASE A2, RE-REFINEMENT OF THE PDB STRUCTURE 1JQ8 WITHOUT THE PUTATIVE COMPLEXED OLIGOPEPTIDE
Descriptor:Phospholipase A2 VRV-PL-VIIIa
Authors:Wlodawer, A., Dauter, Z., Minor, W., Stanfield, R., Porebski, P., Jaskolski, M., Pozharski, E., Weichenberger, C.X., Rupp, B.
Deposit date:2017-04-05
Release date:2018-06-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Detect, correct, retract: How to manage incorrect structural models.
FEBS J., 285, 2018