1KPM
First Structural Evidence of a Specific Inhibition of Phospholipase A2 by Vitamin E and its Implications in Inflammation: Crystal Structure of the Complex Formed between Phospholipase A2 and Vitamin E at 1.8 A Resolution.
Replaces: 1FE7Summary for 1KPM
Entry DOI | 10.2210/pdb1kpm/pdb |
Related | 1CL5 1FB2 1FE7 1FV0 1JQ8 1JQ9 |
Descriptor | Phospholipase A2, VITAMIN E, ACETIC ACID, ... (4 entities in total) |
Functional Keywords | phospholipase a2, daboia russelli pulchella, neurotoxic, inflammation, hydrolase |
Biological source | Daboia russellii pulchella |
Cellular location | Secreted : P59071 |
Total number of polymer chains | 2 |
Total formula weight | 27930.45 |
Authors | Chandra, V.,Jasti, J.,Kaur, P.,Betzel, C.,Srinivasan, A.,Singh, T.P. (deposition date: 2002-01-01, release date: 2002-07-10, Last modification date: 2023-08-16) |
Primary citation | Chandra, V.,Jasti, J.,Kaur, P.,Betzel, C.,Srinivasan, A.,Singh, T.P. First Structural Evidence of a Specific Inhibition of Phospholipase A2 by alpha-Tocopherol (Vitamin E) and its Implications in Inflammation: Crystal Structure of the Complex Formed Between Phospholipase A2 and alpha-Tocopherol at 1.8 A Resolution J.Mol.Biol., 320:215-222, 2002 Cited by PubMed: 12079380DOI: 10.1016/S0022-2836(02)00473-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report