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5DFR
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CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Descriptor:DIHYDROFOLATE REDUCTASE, CHLORIDE ION
Authors:Bystroff, C., Kraut, J.
Deposit date:1988-10-21
Release date:1990-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30, 1991
6DFR
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CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. THE NADP+ HOLOENZYME AND THE FOLATE(DOT)NADP+ TERNARY COMPLEX. SUBSTRATE BINDING AND A MODEL FOR THE TRANSITION STATE
Descriptor:DIHYDROFOLATE REDUCTASE, CALCIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Bystroff, C., Oatley, S.J., Kraut, J.
Deposit date:1988-10-21
Release date:1990-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Escherichia coli dihydrofolate reductase: the NADP+ holoenzyme and the folate.NADP+ ternary complex. Substrate binding and a model for the transition state.
Biochemistry, 29, 1990
7DFR
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CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. THE NADP+ HOLOENZYME AND THE FOLATE(DOT)NADP+ TERNARY COMPLEX. SUBSTRATE BINDING AND A MODEL FOR THE TRANSITION STATE
Descriptor:DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Bystroff, C., Oatley, S.J., Kraut, J.
Deposit date:1988-10-21
Release date:1990-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of Escherichia coli dihydrofolate reductase: the NADP+ holoenzyme and the folate.NADP+ ternary complex. Substrate binding and a model for the transition state.
Biochemistry, 29, 1990
4LW5
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CRYSTAL STRUCTURE OF ALL-TRANS GREEN FLUORESCENT PROTEIN
Descriptor:Green fluorescent protein
Authors:Rosenman, D.J., Huang, Y.-M., Xia, K., Vanroey, P., Colon, W., Bystroff, C.
Deposit date:2013-07-26
Release date:2014-02-05
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Green-lighting green fluorescent protein: Faster and more efficient folding by eliminating a cis-trans peptide isomerization event.
Protein Sci., 23, 2014
1DRB
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CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Descriptor:DIHYDROFOLATE REDUCTASE, CHLORIDE ION, METHOTREXATE, ...
Authors:David, C., Kraut, J.
Deposit date:1991-11-06
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30, 1991
1DRA
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CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Descriptor:DIHYDROFOLATE REDUCTASE, CHLORIDE ION, METHOTREXATE, ...
Authors:Oatley, S.J., Kraut, J.
Deposit date:1991-11-06
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30, 1991
4LQT
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1.10A RESOLUTION CRYSTAL STRUCTURE OF A SUPERFOLDER GREEN FLUORESCENT PROTEIN (W57A) MUTANT
Descriptor:Green fluorescent protein, 1,2-ETHANEDIOL
Authors:Lovell, S., Xia, Y., Vo, B., Battaile, K.P., Egan, C., Karanicolas, J.
Deposit date:2013-07-19
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.
J.Am.Chem.Soc., 135, 2013
4LQU
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1.60A RESOLUTION CRYSTAL STRUCTURE OF A SUPERFOLDER GREEN FLUORESCENT PROTEIN (W57G) MUTANT
Descriptor:Green fluorescent protein
Authors:Lovell, S., Xia, Y., Vo, B., Battaile, K.P., Egan, C., Karanicolas, J.
Deposit date:2013-07-19
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.
J.Am.Chem.Soc., 135, 2013
1ST3
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THE CRYSTAL STRUCTURE OF THE BACILLUS LENTUS ALKALINE PROTEASE, SUBTILISIN BL, AT 1.4 ANGSTROMS RESOLUTION
Descriptor:SUBTILISIN BL, CALCIUM ION
Authors:Goddette, D.W.
Deposit date:1991-11-22
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The crystal structure of the Bacillus lentus alkaline protease, subtilisin BL, at 1.4 A resolution.
J.Mol.Biol., 228, 1992
1DRE
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor:DIHYDROFOLATE REDUCTASE, METHOTREXATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-11-28
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1DRH
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ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS
Descriptor:DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1994-11-30
Release date:1995-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
Biochemistry, 34, 1995
1DYH
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ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS
Descriptor:DIHYDROFOLATE REDUCTASE, CHLORIDE ION, 5-DEAZAFOLIC ACID, ...
Authors:Reyes, V.M., Kraut, J.
Deposit date:1994-10-26
Release date:1995-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
Biochemistry, 34, 1995
1DYI
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ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS
Descriptor:DIHYDROFOLATE REDUCTASE, CHLORIDE ION, FOLIC ACID, ...
Authors:Reyes, V.M., Kraut, J.
Deposit date:1994-10-26
Release date:1995-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
Biochemistry, 34, 1995
1DYJ
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ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS
Descriptor:DIHYDROFOLATE REDUCTASE, CHLORIDE ION, 5,10-DIDEAZATETRAHYDROFOLIC ACID, ...
Authors:Reyes, V.M., Kraut, J.
Deposit date:1994-10-26
Release date:1995-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
Biochemistry, 34, 1995
1JOL
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THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE
Descriptor:DIHYDROFOLATE REDUCTASE, CHLORIDE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ...
Authors:Lee, H., Reyes, V.M., Kraut, J.
Deposit date:1996-02-25
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4.
Biochemistry, 35, 1996
1JOM
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THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE
Descriptor:DIHYDROFOLATE REDUCTASE, CHLORIDE ION, CALCIUM ION, ...
Authors:Reyes, V.M., Lee, H., Kraut, J.
Deposit date:1996-02-25
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4.
Biochemistry, 35, 1996
1RA1
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM)
Descriptor:DIHYDROFOLATE REDUCTASE, CALCIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-10-30
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RA2
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor:DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-10-28
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RA3
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor:DIHYDROFOLATE REDUCTASE, METHOTREXATE, BETA-MERCAPTOETHANOL, ...
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-10-28
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RA8
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 2-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE
Descriptor:DIHYDROFOLATE REDUCTASE, FOLIC ACID, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-11-21
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RA9
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor:DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-10-28
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RB2
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor:DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-11-26
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RB3
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor:DIHYDROFOLATE REDUCTASE, METHOTREXATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-11-26
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RC4
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor:DIHYDROFOLATE REDUCTASE, 5,10-DIDEAZATETRAHYDROFOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-11-25
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RD7
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE
Descriptor:DIHYDROFOLATE REDUCTASE, FOLIC ACID, BETA-MERCAPTOETHANOL
Authors:Sawaya, M.R., Kraut, J.
Deposit date:1996-11-01
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
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