1DYH

ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS

Summary for 1DYH

DescriptorDIHYDROFOLATE REDUCTASE, CHLORIDE ION, 5-DEAZAFOLIC ACID, ... (5 entities in total)
Functional Keywordsoxidoreductase
Biological sourceEscherichia coli
Total number of polymer chains2
Total molecular weight37032.45
Authors
Reyes, V.M.,Kraut, J. (deposition date: 1994-10-26, release date: 1995-06-03, Last modification date: 2011-07-13)
Primary citation
Reyes, V.M.,Sawaya, M.R.,Brown, K.A.,Kraut, J.
Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
Biochemistry, 34:2710-2723, 1995
PubMed: 7873554 (PDB entries with the same primary citation)
DOI: 10.1021/bi00008a039
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers120.6%8.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1dyh
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Molmil generated image of 1dyh
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Molmil generated image of 1dyh
rotated about y axis by 90°