7DFR

CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. THE NADP+ HOLOENZYME AND THE FOLATE(DOT)NADP+ TERNARY COMPLEX. SUBSTRATE BINDING AND A MODEL FOR THE TRANSITION STATE

Summary for 7DFR

DescriptorDIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
Functional Keywordsoxido-reductase, oxidoreductase
Biological sourceEscherichia coli
Total number of polymer chains1
Total molecular weight19205.13
Authors
Bystroff, C.,Oatley, S.J.,Kraut, J. (deposition date: 1988-10-21, release date: 1990-07-15, Last modification date: 2017-11-29)
Primary citation
Bystroff, C.,Oatley, S.J.,Kraut, J.
Crystal structures of Escherichia coli dihydrofolate reductase: the NADP+ holoenzyme and the folate.NADP+ ternary complex. Substrate binding and a model for the transition state.
Biochemistry, 29:3263-3277, 1990
PubMed: 2185835 (PDB entries with the same primary citation)
DOI: 10.1021/bi00465a018
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers533.2%14.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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