7DFR
CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. THE NADP+ HOLOENZYME AND THE FOLATE(DOT)NADP+ TERNARY COMPLEX. SUBSTRATE BINDING AND A MODEL FOR THE TRANSITION STATE
Summary for 7DFR
Entry DOI | 10.2210/pdb7dfr/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | oxido-reductase, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 19205.13 |
Authors | Bystroff, C.,Oatley, S.J.,Kraut, J. (deposition date: 1988-10-21, release date: 1990-07-15, Last modification date: 2017-11-29) |
Primary citation | Bystroff, C.,Oatley, S.J.,Kraut, J. Crystal structures of Escherichia coli dihydrofolate reductase: the NADP+ holoenzyme and the folate.NADP+ ternary complex. Substrate binding and a model for the transition state. Biochemistry, 29:3263-3277, 1990 Cited by PubMed: 2185835DOI: 10.1021/bi00465a018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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