1RE7
DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE
Summary for 1RE7
Entry DOI | 10.2210/pdb1re7/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE, FOLIC ACID (3 entities in total) |
Functional Keywords | oxidoreductase, nadp, trimethoprim resistance, methotrexate resistance, one-carbon metabolism |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 36923.45 |
Authors | Sawaya, M.R. (deposition date: 1996-11-01, release date: 1996-12-23, Last modification date: 2024-05-22) |
Primary citation | Sawaya, M.R.,Kraut, J. Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36:586-603, 1997 Cited by PubMed: 9012674DOI: 10.1021/bi962337c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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