5DFR
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Summary for 5DFR
Entry DOI | 10.2210/pdb5dfr/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE, CHLORIDE ION (3 entities in total) |
Functional Keywords | oxido-reductase, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 18126.69 |
Authors | Bystroff, C.,Kraut, J. (deposition date: 1988-10-21, release date: 1990-07-15, Last modification date: 2024-03-06) |
Primary citation | Bystroff, C.,Kraut, J. Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding. Biochemistry, 30:2227-2239, 1991 Cited by PubMed: 1998681DOI: 10.1021/bi00222a028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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