Author results

5OLF
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LIGAND-BASED NMR STUDY OF C-X-C CHEMOKINE RECEPTOR TYPE 4 (CXCR4)-LIGAND INTERACTIONS IN LIVING CANCER CELLS
Descriptor:GBA-ALA-CYS-ARG-PHE-PHE-CYS
Authors:Brancaccio, D., Carotenuto, A.
Deposit date:2017-07-27
Release date:2018-06-06
Method:SOLUTION NMR
Cite:Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells.
J. Med. Chem., 61, 2018
6HVB
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NMR STRUCTURE OF UROTENSIN PEPTIDE ASP-C[CYS-PHE-(N-ME)TRP-LYS-TYR-CYS]-VAL IN SDS SOLUTION
Descriptor:Urotensin-2
Authors:Brancaccio, D., Carotenuto, A., Merlino, F., Billard, E., Yousif, A.M., Di Maro, S., Abate, L., Bellavita, R., D'Emmanuele di Villa Bianca, R., Santicioli, P., Marinelli, L., Novellino, E., Hebert, T.E., Lubell, W.D., Chatenet, D., Grieco, P.
Deposit date:2018-10-10
Release date:2019-01-16
Method:SOLUTION NMR
Cite:Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides.
J. Med. Chem., 2019
6HVC
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NMR STRUCTURE OF UROTENSIN PEPTIDE ASP-C[CYS-PHE-TRP-(N-ME)LYS-TYR-CYS]-VAL IN SDS SOLUTION
Descriptor:Urotensin-2
Authors:Brancaccio, D., Carotenuto, A., Merlino, F., Billard, E., Yousif, A.M., Di Maro, S., Abate, L., Bellavita, R., D'Emmanuele di Villa Bianca, R., Santicioli, P., Marinelli, L., Novellino, E., Hebert, T.E., Lubell, W.D., Chatenet, D., Grieco, P.
Deposit date:2018-10-10
Release date:2019-01-16
Method:SOLUTION NMR
Cite:Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides.
J. Med. Chem., 2019
5OJT
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STRUCTURE-ACTIVITY RELATIONSHIPS AND BIOLOGICAL CHARACTERIZATION OF A NOVEL, POTENT AND SERUM STABLE C-X-C CHEMOKINE RECEPTOR TYPE 4 (CXCR4) ANTAGONIST
Descriptor:ACE-ARG-ALA-(D)CYS-ARG-BNA-HIS-PEN
Authors:Brancaccio, D., Carotenuto, A.
Deposit date:2017-07-24
Release date:2017-11-22
Last modified:2017-12-27
Method:SOLUTION NMR
Cite:Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist.
J. Med. Chem., 60, 2017
6FCE
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NMR ENSEMBLE OF MACROCYCLIC PEPTIDOMIMETIC CONTAINING CONSTRAINED A,A-DIALKYLATED AMINO ACIDS WITH POTENT AND SELECTIVE ACTIVITY AT HUMAN MELANOCORTIN RECEPTORS
Descriptor:ACP-HIS-DPHE-ARG-TRP-ASP-NH2
Authors:Brancaccio, D., Carotenuto, A., Grieco, P., Merlino, F., Zhou, Y., Cai, M., Yousif, A.M., Di Maro, S., Novellino, E., Hruby, V.J.
Deposit date:2017-12-20
Release date:2018-04-25
Last modified:2018-05-23
Method:SOLUTION NMR
Cite:Development of Macrocyclic Peptidomimetics Containing Constrained alpha , alpha-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors.
J. Med. Chem., 61, 2018
5LFF
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NMR STRUCTURE OF PEPTIDE 2 TARGETING CXCR4
Descriptor:ARG-ALA-CYS-ARG-PHE-PHE-CYS
Authors:Di Maro, S., Trotta, A.M., Brancaccio, D., Di Leva, F.S., La Pietra, V., Ierano, C., Napolitano, M., Portella, L., D'Alterio, C., Siciliano, R.A., Sementa, D., Tomassi, S., Carotenuto, A., Novellino, E., Scala, S., Marinelli, L.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2016-10-05
Method:SOLUTION NMR
Cite:Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists.
J.Med.Chem., 59, 2016
5LFH
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NMR STRUCTURE OF PEPTIDE 10 TARGETING CXCR4
Descriptor:ACE-ARG-ALA-DCY-ARG-PHE-PHE-CYS
Authors:Di Maro, S., Trotta, A.M., Brancaccio, D., Di Leva, F.S., La Pietra, V., Ierano, C., Napolitano, M., Portella, L., D'Alterio, C., Siciliano, R.A., Sementa, D., Tomassi, S., Carotenuto, A., Novellino, E., Scala, S., Marinelli, L.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2016-10-05
Method:SOLUTION NMR
Cite:Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists.
J.Med.Chem., 59, 2016
2MMZ
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SOLUTION STRUCTURE OF THE APO FORM OF HUMAN GLUTAREDOXIN 5
Descriptor:Glutaredoxin-related protein 5, mitochondrial
Authors:Banci, L., Brancaccio, D., Ciofi-Baffoni, S., Del Conte, R., Gadepalli, R., Mikolajczyk, M., Neri, S., Piccioli, M., Winkelmann, J.
Deposit date:2014-03-25
Release date:2014-04-16
Last modified:2014-05-21
Method:SOLUTION NMR
Cite:[2Fe-2S] cluster transfer in iron-sulfur protein biogenesis.
Proc.Natl.Acad.Sci.USA, 111, 2014
2N7N
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NMR STRUCTURE OF PEPTIDE PG-989 IN DPC MICELLES
Descriptor:Peptide PG-989
Authors:Carotenuto, A., Merlino, F., Chai, M., Brancaccio, D., Yousif, A., Novellino, E., Hruby, V., Grieco, P.
Deposit date:2015-09-16
Release date:2015-12-16
Last modified:2017-10-11
Method:SOLUTION NMR
Cite:Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor.
J.Med.Chem., 58, 2015
2N7O
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NMR STRUCTURE OF PEPTIDE PG-990 IN DPC MICELLES
Descriptor:Peptide PG-990
Authors:Carotenuto, A., Merlino, F., Chai, M., Brancaccio, D., Yousif, A., Novellino, E., Hruby, V., Grieco, P.
Deposit date:2015-09-16
Release date:2015-12-16
Last modified:2017-10-11
Method:SOLUTION NMR
Cite:Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor.
J.Med.Chem., 58, 2015
2N7T
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NMR STRUCTURE OF PEPTIDE PG-992 IN DPC MICELLES
Descriptor:Peptide PG-992
Authors:Carotenuto, A., Merlino, F., Chai, M., Brancaccio, D., Yousif, A., Novellino, E., Hruby, V., Grieco, P.
Deposit date:2015-09-17
Release date:2015-12-16
Last modified:2017-10-11
Method:SOLUTION NMR
Cite:Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor.
J.Med.Chem., 58, 2015
1JNJ
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NMR SOLUTION STRUCTURE OF THE HUMAN BETA2-MICROGLOBULIN
Descriptor:beta2-microglobulin
Authors:Verdone, G., Corazza, A., Viglino, P., Pettirossi, F., Giorgetti, S., Mangione, P., Andreola, A., Stoppini, M., Bellotti, V., Esposito, G.
Deposit date:2001-07-24
Release date:2002-02-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition.
Protein Sci., 11, 2002