6QXB

NMR structure of peptide 7, characterized by a cis-4-amino-Pro residue, with a significant lower MIC on E. coli

Summary for 6QXB

• Entry DOI: 10.2210/pdb6qxb/pdb
• NMR Information: BMRB: 34366
• Descriptor: PHE-VAL-CAP-TRP-PHE-SER-LYS-PHE-LEU-GLY-ARG-ILE-LEU-NH2 (1 entity in total)
• Functional Keywords: peptide antimicrobial, amps, temporins, proline derivatives, antibiotic
• Biological source: Pseudis bolbodactyla
• Total number of polymer chains: 1
• Total formula weight: 1626.00

Authors

Brancaccio, D.,Carotenuto, A.,Merlino, F.,Grieco, P.,Novellino, E. (deposition date: 2019-03-07, release date: 2019-05-29, Last modification date: 2023-06-14)

• Primary citation: Buommino, E.,Carotenuto, A.,Antignano, I.,Bellavita, R.,Casciaro, B.,Loffredo, M.R.,Merlino, F.,Novellino, E.,Mangoni, M.L.,Nocera, F.P.,Brancaccio, D.,Punzi, P.,Roversi, D.,Ingenito, R.,Bianchi, E.,Grieco, P.; The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L.; Chemmedchem, 14:1283-1290, 2019; PubMed: 31087626; DOI: 10.1002/cmdc.201900221

Experimental method

SOLUTION NMR