7OSD

NMR Solution Structure of Peptide 12: First-in-class cyclic Temporin L analogue with antibacterial and antibiofilm activities

Summary for 7OSD

• Entry DOI: 10.2210/pdb7osd/pdb
• NMR Information: BMRB: 34634
• Descriptor: PHE-VAL-PRO-TRP-PHE-LYS-LYS-PHE-DLE-GLU-ARG-ILE-LEU-NH2 (1 entity in total)
• Functional Keywords: temporins, antimicrobial, antimicrobial protein
• Biological source: Rana temporaria
• Total number of polymer chains: 1
• Total formula weight: 1724.14

Authors

Brancaccio, D.,Carotenuto, A. (deposition date: 2021-06-08, release date: 2021-08-11, Last modification date: 2021-08-25)

• Primary citation: Bellavita, R.,Casciaro, B.,Di Maro, S.,Brancaccio, D.,Carotenuto, A.,Falanga, A.,Cappiello, F.,Buommino, E.,Galdiero, S.,Novellino, E.,Grossmann, T.N.,Mangoni, M.L.,Merlino, F.,Grieco, P.; First-in-Class Cyclic Temporin L Analogue: Design, Synthesis, and Antimicrobial Assessment.; J.Med.Chem., 64:11675-11694, 2021; PubMed: 34296619; DOI: 10.1021/acs.jmedchem.1c01033

Experimental method

SOLUTION NMR