6QMQ

NF-YB/C Heterodimer in Complex with NF-YA-derived Peptide Stabilized with C8-Hydrocarbon Linker

Summary for 6QMQ

Entry DOI	10.2210/pdb6qmq/pdb
Descriptor	Nuclear transcription factor Y subunit alpha, Nuclear transcription factor Y subunit beta, Nuclear transcription factor Y subunit gamma, ... (5 entities in total)
Functional Keywords	stapled peptide histone fold transcription factor, transcription
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	24527.60
Authors	Kiehstaller, S.,Jeganathan, S.,Pearce, N.M.,Wendt, M.,Grossmann, T.N.,Hennig, S. (deposition date: 2019-02-08, release date: 2019-10-02, Last modification date: 2024-01-24)
Primary citation	Jeganathan, S.,Wendt, M.,Kiehstaller, S.,Brancaccio, D.,Kuepper, A.,Pospiech, N.,Carotenuto, A.,Novellino, E.,Hennig, S.,Grossmann, T.N. Constrained Peptides with Fine-Tuned Flexibility Inhibit NF-Y Transcription Factor Assembly. Angew.Chem.Int.Ed.Engl., 58:17351-17358, 2019 Cited by PubMed: 31539186 DOI: 10.1002/anie.201907901 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation