6QMQ

NF-YB/C Heterodimer in Complex with NF-YA-derived Peptide Stabilized with C8-Hydrocarbon Linker

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Nuclear transcription factor Y subunit alpha	polymer	21	2369.9	1	UniProt (P23511) Pfam (PF02045) In PDB	Homo sapiens	CAAT box DNA-binding protein subunit A,Nuclear transcription factor Y subunit A,NF-YA
2	B	Nuclear transcription factor Y subunit beta	polymer	95	10876.5	1	UniProt (P25208) Pfam (PF00808) In PDB	Homo sapiens (human)	CAAT box DNA-binding protein subunit B,Nuclear transcription factor Y subunit B,NF-YB
3	C	Nuclear transcription factor Y subunit gamma	polymer	96	11258.2	1	UniProt (Q13952) Pfam (PF00125) In PDB	Homo sapiens (human)	CAAT box DNA-binding protein subunit C,Nuclear transcription factor Y subunit C,NF-YC,Transactivator HSM-1/2
4	C	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5		water	water		18.0	7	Chemie (HOH)

Sequence modifications

A: 302 - 320 (UniProt: P23511)

PDB	External Database	Details
Ace 301	-	acetylation
Ic0 307	Tyr 272	engineered mutation
Mh8 311	Leu 276	engineered mutation
Nh2 321	-	amidation

B: 51 - 143 (UniProt: P25208)

PDB	External Database	Details
Gly 49	-	expression tag
Pro 50	-	expression tag

C: 27 - 120 (UniProt: Q13952)

PDB	External Database	Details
Gly 25	-	expression tag
Pro 26	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	24504.6
Non-Polymers*	Number of molecules	1
	Total formula weight	23.0
All*	Total formula weight	24527.6

*Water molecules are not included.