Author results

2PZH
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YBGC THIOESTERASE (HP0496) FROM HELICOBACTER PYLORI
Descriptor:Hypothetical protein HP_0496
Authors:Angelini, A., Cendron, L., Goncalves, S., Zanotti, G., Terradot, L.
Deposit date:2007-05-18
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and enzymatic characterization of HP0496, a YbgC thioesterase from Helicobacter pylori.
Proteins, 72, 2008
3QN7
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POTENT AND SELECTIVE BICYCLIC PEPTIDE INHIBITOR (UK18) OF HUMAN UROKINASE-TYPE PLASMINOGEN ACTIVATOR(UPA)
Descriptor:Urokinase-type plasminogen activator, Bicyclic peptide inhibitor, 1,3,5-tris(bromomethyl)benzene
Authors:Angelini, A., Cendron, L., Touati, J., Winter, G., Zanotti, G., Heinis, C.
Deposit date:2011-02-08
Release date:2012-02-15
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Bicyclic peptide inhibitor reveals large contact interface with a protease target
Acs Chem.Biol., 7, 2012
3CWX
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CRYSTAL STRUCTURE OF CAGD FROM HELICOBACTER PYLORI PATHOGENICITY ISLAND
Descriptor:protein CagD
Authors:Cendron, L., Zanotti, G., Angelini, A., Barison, N., Couturier, M., Stein, M.
Deposit date:2008-04-23
Release date:2008-12-30
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion.
J.Mol.Biol., 386, 2009
3CWY
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STRUCTURE OF CAGD FROM H. PYLORI PATHOGENICITY ISLAND CRYSTALLIZED IN THE PRESENCE OF CU(II) IONS
Descriptor:protein CagD, COPPER (II) ION
Authors:Cendron, L., Zanotti, G., Angelini, A., Barison, N., Couturier, M., Stein, M.
Deposit date:2008-04-23
Release date:2008-12-30
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion.
J.Mol.Biol., 386, 2009
2G3V
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CRYSTAL STRUCTURE OF CAGS (HP0534, CAG13) FROM HELICOBACTER PYLORI
Descriptor:CAG pathogenicity island protein 13, (UNK)(UNK)(UNK)(UNK)(UNK)(MSE)(UNK)
Authors:Cendron, L., Tasca, E., Angelini, A., Seydel, A., Battistutta, R., Montecucco, C., Zanotti, G.
Deposit date:2006-02-21
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of CagS from helicobacter pylori
To be Published
1S2X
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CRYSTAL STRUCTURE OF CAG-Z FROM HELICOBACTER PYLORI
Descriptor:Cag-Z, ISOPROPYL ALCOHOL
Authors:Cendron, L., Seydel, A., Angelini, A., Battistutta, R., Zanotti, G.
Deposit date:2004-01-12
Release date:2004-07-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system
J.Mol.Biol., 340, 2004
2RD3
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CRYSTAL STRUCTURE OF TENA HOMOLOGUE (HP1287) FROM HELICOBACTER PYLORI
Descriptor:Transcriptional regulator
Authors:Barison, N., Cendron, L., Trento, A., Angelini, A., Zanotti, G.
Deposit date:2007-09-21
Release date:2008-09-30
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural and functional characterization of HP1287 from Helicobacter pylori demonstrates it is a TenA homologue
To be Published
3IBX
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CRYSTAL STRUCTURE OF F47Y VARIANT OF TENA (HP1287) FROM HELICOBACTER PYLORI
Descriptor:Putative thiaminase II
Authors:Barison, N., Cendron, L., Trento, A., Angelini, A., Zanotti, G.
Deposit date:2009-07-17
Release date:2009-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and mutational analysis of TenA protein (HP1287) from the Helicobacter pylori thiamin salvage pathway - evidence of a different substrate specificity.
Febs J., 276, 2009
4IE9
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BOVINE PKA C-ALPHA IN COMPLEX WITH 3-PYRIDYLMETHYL-5-METHYL-1H-PYRAZOLE-3-CARBOXYLATE
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, pyridin-3-ylmethyl 5-methyl-1H-pyrazole-3-carboxylate, ...
Authors:Dreyer, M.K., Schiffer, A., Lodge, J.
Deposit date:2012-12-13
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Accounting for Conformational Variability in Protein-Ligand Docking with NMR-Guided Rescoring
J.Am.Chem.Soc., 135, 2013
4IJ9
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BOVINE PKA C-ALPHA IN COMPLEX WITH 2-[[5-(4-PYRIDYL)-1H-1,2,4-TRIAZOL-3-YL]SULFANYL]-1-(2-THIOPHENYL)ETHANONE
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 2-[[5-(4-pyridyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-(2-thiophenyl)ethanone
Authors:Dreyer, M.K., Schiffer, A.
Deposit date:2012-12-21
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Accounting for Conformational Variability in Protein-Ligand Docking with NMR-Guided Rescoring
J.Am.Chem.Soc., 135, 2013
4XT1
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STRUCTURE OF A NANOBODY-BOUND VIRAL GPCR BOUND TO HUMAN CHEMOKINE CX3CL1
Descriptor:G-protein coupled receptor homolog US28, Fractalkine, nanobody 7, ...
Authors:Burg, J.S., Jude, K.M., Waghray, D., Garcia, K.C.
Deposit date:2015-01-22
Release date:2015-03-04
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.886 Å)
Cite:Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
4XT3
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STRUCTURE OF A VIRAL GPCR BOUND TO HUMAN CHEMOKINE CX3CL1
Descriptor:G-protein coupled receptor homolog US28, Fractalkine, UNKNOWN LIGAND, ...
Authors:Burg, J.S., Jude, K.M., Waghray, D., Garcia, K.C.
Deposit date:2015-01-22
Release date:2015-03-04
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (3.801 Å)
Cite:Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
4MNV
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CRYSTAL STRUCTURE OF BICYCLIC PEPTIDE UK729 BOUND AS AN ACYL-ENZYME INTERMEDIATE TO UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA)
Descriptor:Urokinase-type plasminogen activator chain B, acyl-enzyme intermediate of bicyclic peptide UK729, SULFATE ION, ...
Authors:Chen, S., Pojer, F., Heinis, C.
Deposit date:2013-09-11
Release date:2014-02-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Peptide ligands stabilized by small molecules.
Angew.Chem.Int.Ed.Engl., 53, 2014
4MNW
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CRYSTAL STRUCTURE OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA) COMPLEXED WITH BICYCLIC PEPTIDE UK749
Descriptor:Urokinase-type plasminogen activator chain B, bicyclic peptide UK749, SULFATE ION, ...
Authors:Chen, S., Pojer, F., Heinis, C.
Deposit date:2013-09-11
Release date:2014-02-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Peptide ligands stabilized by small molecules.
Angew.Chem.Int.Ed.Engl., 53, 2014
4MNX
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CRYSTAL STRUCTURE OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA) COMPLEXED WITH BICYCLIC PEPTIDE UK811
Descriptor:Urokinase-type plasminogen activator chain B, bicyclic peptide UK811, SULFATE ION, ...
Authors:Chen, S., Pojer, F., Heinis, C.
Deposit date:2013-09-11
Release date:2014-02-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Peptide ligands stabilized by small molecules.
Angew.Chem.Int.Ed.Engl., 53, 2014
4MNY
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CRYSTAL STRUCTURE OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA) COMPLEXED WITH BICYCLIC PEPTIDE UK903
Descriptor:Urokinase-type plasminogen activator chain B, bicyclic peptide UK903, SULFATE ION, ...
Authors:Chen, S., Pojer, F., Heinis, C.
Deposit date:2013-09-11
Release date:2014-02-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Peptide ligands stabilized by small molecules.
Angew.Chem.Int.Ed.Engl., 53, 2014