7B5G

Crystal structure of E.coli LexA in complex with nanobody NbSOS3(Nb14527)

Summary for 7B5G

Entry DOI	10.2210/pdb7b5g/pdb
Descriptor	LexA repressor, Nanobody Nb14527, NbSOS3, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	transcriptional repressor dna binding autoproteolysis nanobodies, transcription
Biological source	Escherichia coli K-12 More
Total number of polymer chains	8
Total formula weight	147125.40
Authors	Maso, L.,Vascon, F.,Chinellato, M.,Pardon, E.,Steyaert, J.,Angelini, A.,Tondi, D.,Cendron, L. (deposition date: 2020-12-03, release date: 2022-09-14, Last modification date: 2024-01-31)
Primary citation	Maso, L.,Vascon, F.,Chinellato, M.,Goormaghtigh, F.,Bellio, P.,Campagnaro, E.,Van Melderen, L.,Ruzzene, M.,Pardon, E.,Angelini, A.,Celenza, G.,Steyaert, J.,Tondi, D.,Cendron, L. Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway. Structure, 30:1479-, 2022 Cited by PubMed: 36240773 DOI: 10.1016/j.str.2022.09.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation