4Q0G | |
5CCA | | CRYSTAL STRUCTURE OF MTB TOXIN | | Descriptor: | Endoribonuclease MazF3 | | Authors: | Cascio, D., Arbing, M., de Serrano, V., Eisenberg, D., Miallau, L., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2015-07-01 | | Release date: | 2016-09-07 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of Mtb toxin
To Be Published
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4GZR | | CRYSTAL STRUCTURE OF THE MYCOBACTERIUM TUBERCULOSIS H37RV ESXOP (RV2346C-RV2347C) COMPLEX IN SPACE GROUP C2221 | | Descriptor: | ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION | | Authors: | Arbing, M.A., Chan, S., He, Q., Harris, L., Zhou, T.T., Kuo, E., Ahn, C.J., Eisenberg, D., TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2012-09-06 | | Release date: | 2012-09-26 | | Last modified: | 2014-05-21 | | Method: | X-RAY DIFFRACTION (2.553 Å) | | Cite: | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
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1QPQ | | STRUCTURE OF QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS: A POTENTIAL TB DRUG TARGET | | Descriptor: | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION, QUINOLINIC ACID | | Authors: | Sharma, V., Grubmeyer, C., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 1998-11-20 | | Release date: | 1998-11-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target.
Structure, 6, 1998
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1QPN | |
1QPO | |
1QPR | | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP | | Descriptor: | QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE, MANGANESE (II) ION, PHTHALIC ACID, ... | | Authors: | Sharma, V., Grubmeyer, C., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 1998-10-17 | | Release date: | 1998-10-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target.
Structure, 6, 1998
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3B4T | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS RNASE PH, THE MYCOBACTERIUM TUBERCULOSIS STRUCTURAL GENOMICS CONSORTIUM TARGET RV1340 | | Descriptor: | Ribonuclease PH, PHOSPHATE ION | | Authors: | Antczak, A.J., Berger, J.M., Lekin, T., Segelke, B.W., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB), TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2007-10-24 | | Release date: | 2007-11-20 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | 2.1 A Crystal structure of RNase PH from Mycobacterium tuberculosis.
To be Published
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1BVR | | M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY-ACYL-SUBSTRATE | | Descriptor: | PROTEIN (ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRANS-2-HEXADECENOYL-(N-ACETYL-CYSTEAMINE)-THIOESTER | | Authors: | Rozwarski, D.A., Vilcheze, C., Sugantino, M., Bittman, R., Jacobs, W., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 1998-09-17 | | Release date: | 1999-09-17 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate.
J.Biol.Chem., 274, 1999
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1NYO | | SOLUTION STRUCTURE OF THE ANTIGENIC TB PROTEIN MPT70/MPB70 | | Descriptor: | Immunogenic protein MPT70 | | Authors: | Bloemink, M.J., Dentten, E., Hewinson, R.G., Williamson, R.A., Carr, M.D., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-02-13 | | Release date: | 2003-08-19 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease
J.Biol.Chem., 278, 2003
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4ISB | |
1MO4 | |
1MO5 | |
1RFE | | CRYSTAL STRUCTURE OF CONSERVED HYPOTHETICAL PROTEIN RV2991 FROM MYCOBACTERIUM TUBERCULOSIS | | Descriptor: | hypothetical protein Rv2991 | | Authors: | Benini, S., Haouz, A., Proux, F., Betton, J.M., Alzari, P., Dodson, G.G., Wilson, K.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-11-08 | | Release date: | 2004-12-28 | | Last modified: | 2019-04-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of Rv2991 from Mycobacterium tuberculosis: An F420binding protein with unknown function.
J. Struct. Biol., 2019
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2FGG | | CRYSTAL STRUCTURE OF RV2632C | | Descriptor: | Hypothetical protein Rv2632c/MT2708 | | Authors: | Yu, M., Bursey, E.H., Radhakannan, T., Segelke, B.W., Lekin, T., Toppani, D., Kim, C.Y., Kaviratne, T., Woodruff, T., Terwilliger, T.C., Hung, L.W., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2005-12-21 | | Release date: | 2006-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Rv2632c
To be Published
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3ERE | | CRYSTAL STRUCTURE OF THE ARGININE REPRESSOR PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH THE DNA OPERATOR | | Descriptor: | Arginine repressor, 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DAP*DAP*DCP*DGP*DAP*DTP*DGP*DCP*DAP*DA)-3', 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DCP*DGP*DTP*DTP*DAP*DTP*DGP*DCP*DAP*DA)-3', ... | | Authors: | Cherney, L.T., Cherney, M.M., Garen, C.R., Lu, G.J., James, M.N., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-10-01 | | Release date: | 2008-10-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis.
J.Mol.Biol., 384, 2008
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3FHZ | | CRYSTAL STRUCTURE OF THE ARGININE REPRESSOR FROM MYCOBACTERIUM TUBERCULOSIS BOUND WITH ITS DNA OPERATOR AND CO-REPRESSOR, L-ARGININE | | Descriptor: | Arginine repressor, 5'-D(*TP*GP*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*AP*CP*A)-3', ... | | Authors: | Cherney, L.T., Cherney, M.M., Garen, C.R., James, M.N.G., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-12-10 | | Release date: | 2009-03-24 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (3.27 Å) | | Cite: | The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine.
J.Mol.Biol., 388, 2009
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4GKM | | BIANTHRANILATE-LIKE ANALOGUE BOUND IN THE OUTER SITE OF ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE (ANPRT; TRPD) | | Descriptor: | Anthranilate phosphoribosyltransferase, ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID, MAGNESIUM ION, ... | | Authors: | Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2012-08-13 | | Release date: | 2013-08-14 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.6683 Å) | | Cite: | Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.
Chembiochem, 15, 2014
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4IJ1 | | BIANTHRANILATE-LIKE ANALOGUE BOUND TO ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE (ANPRT; TRPD) IN ABSENCE OF SUBSTRATES. | | Descriptor: | Anthranilate phosphoribosyltransferase, 2,2'-iminodibenzoic acid, GLYCEROL, ... | | Authors: | Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2012-12-20 | | Release date: | 2013-12-25 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.
Chembiochem, 15, 2014
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4XRB | |
4XT4 | | CRYSTAL STRUCTURE OF RV2671 FROM MYCOBACTEIRUM TUBERCULOSIS IN COMPLEX WITH DIHYDROPTERIDINE RING OF DIHYDROPTEROIC ACID | | Descriptor: | Rv2671, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-amino-6-methyl-7,8-dihydropteridin-4(3H)-one, ... | | Authors: | Sacchettini, J.C., Cheng, Y.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2015-01-22 | | Release date: | 2016-02-24 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (1.891 Å) | | Cite: | Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance.
Biochemistry, 55, 2016
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4XT5 | |
4XT6 | | CRYSTAL STRUCTURE OF RV2671 FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH THE TETRAHYDROPTERIDINE RING OF TETRAHYDROFOLATE (THF) | | Descriptor: | Rv2671, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (6S)-2-amino-6-methyl-5,6,7,8-tetrahydropteridin-4(3H)-one | | Authors: | Sacchettini, J.C., Cheng, Y.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2015-01-23 | | Release date: | 2016-02-24 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance.
Biochemistry, 55, 2016
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4XT7 | |
4XT8 | |
