4Q0G | |
5CCA | | CRYSTAL STRUCTURE OF MTB TOXIN | | Descriptor: | Endoribonuclease MazF3 | | Authors: | Cascio, D., Arbing, M., de Serrano, V., Eisenberg, D., Miallau, L., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2015-07-01 | | Release date: | 2016-09-07 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of Mtb toxin
To Be Published
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1QPQ | | STRUCTURE OF QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS: A POTENTIAL TB DRUG TARGET | | Descriptor: | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION, QUINOLINIC ACID | | Authors: | Sharma, V., Grubmeyer, C., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 1998-11-20 | | Release date: | 1998-11-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target.
Structure, 6, 1998
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4GZR | | CRYSTAL STRUCTURE OF THE MYCOBACTERIUM TUBERCULOSIS H37RV ESXOP (RV2346C-RV2347C) COMPLEX IN SPACE GROUP C2221 | | Descriptor: | ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION | | Authors: | Arbing, M.A., Chan, S., He, Q., Harris, L., Zhou, T.T., Kuo, E., Ahn, C.J., Eisenberg, D., TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2012-09-06 | | Release date: | 2012-09-26 | | Last modified: | 2014-05-21 | | Method: | X-RAY DIFFRACTION (2.553 Å) | | Cite: | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
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1QPN | |
1QPO | |
1QPR | | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP | | Descriptor: | QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE, MANGANESE (II) ION, PHTHALIC ACID, ... | | Authors: | Sharma, V., Grubmeyer, C., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 1998-10-17 | | Release date: | 1998-10-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target.
Structure, 6, 1998
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3B4T | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS RNASE PH, THE MYCOBACTERIUM TUBERCULOSIS STRUCTURAL GENOMICS CONSORTIUM TARGET RV1340 | | Descriptor: | Ribonuclease PH, PHOSPHATE ION | | Authors: | Antczak, A.J., Berger, J.M., Lekin, T., Segelke, B.W., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB), TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2007-10-24 | | Release date: | 2007-11-20 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | 2.1 A Crystal structure of RNase PH from Mycobacterium tuberculosis.
To be Published
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1BVR | | M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY-ACYL-SUBSTRATE | | Descriptor: | PROTEIN (ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRANS-2-HEXADECENOYL-(N-ACETYL-CYSTEAMINE)-THIOESTER | | Authors: | Rozwarski, D.A., Vilcheze, C., Sugantino, M., Bittman, R., Jacobs, W., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 1998-09-17 | | Release date: | 1999-09-17 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate.
J.Biol.Chem., 274, 1999
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1NYO | | SOLUTION STRUCTURE OF THE ANTIGENIC TB PROTEIN MPT70/MPB70 | | Descriptor: | Immunogenic protein MPT70 | | Authors: | Bloemink, M.J., Dentten, E., Hewinson, R.G., Williamson, R.A., Carr, M.D., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-02-13 | | Release date: | 2003-08-19 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease
J.Biol.Chem., 278, 2003
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4ISB | |
1RFE | | CRYSTAL STRUCTURE OF CONSERVED HYPOTHETICAL PROTEIN RV2991 FROM MYCOBACTERIUM TUBERCULOSIS | | Descriptor: | hypothetical protein Rv2991 | | Authors: | Benini, S., Haouz, A., Proux, F., Betton, J.M., Alzari, P., Dodson, G.G., Wilson, K.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-11-08 | | Release date: | 2004-12-28 | | Last modified: | 2019-04-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of Rv2991 from Mycobacterium tuberculosis: An F420binding protein with unknown function.
J. Struct. Biol., 2019
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2FGG | | CRYSTAL STRUCTURE OF RV2632C | | Descriptor: | Hypothetical protein Rv2632c/MT2708 | | Authors: | Yu, M., Bursey, E.H., Radhakannan, T., Segelke, B.W., Lekin, T., Toppani, D., Kim, C.Y., Kaviratne, T., Woodruff, T., Terwilliger, T.C., Hung, L.W., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2005-12-21 | | Release date: | 2006-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Rv2632c
To be Published
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3ERE | | CRYSTAL STRUCTURE OF THE ARGININE REPRESSOR PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH THE DNA OPERATOR | | Descriptor: | Arginine repressor, 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DAP*DAP*DCP*DGP*DAP*DTP*DGP*DCP*DAP*DA)-3', 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DCP*DGP*DTP*DTP*DAP*DTP*DGP*DCP*DAP*DA)-3', ... | | Authors: | Cherney, L.T., Cherney, M.M., Garen, C.R., Lu, G.J., James, M.N., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-10-01 | | Release date: | 2008-10-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis.
J.Mol.Biol., 384, 2008
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3FHZ | | CRYSTAL STRUCTURE OF THE ARGININE REPRESSOR FROM MYCOBACTERIUM TUBERCULOSIS BOUND WITH ITS DNA OPERATOR AND CO-REPRESSOR, L-ARGININE | | Descriptor: | Arginine repressor, 5'-D(*TP*GP*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*AP*CP*A)-3', ... | | Authors: | Cherney, L.T., Cherney, M.M., Garen, C.R., James, M.N.G., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-12-10 | | Release date: | 2009-03-24 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (3.27 Å) | | Cite: | The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine.
J.Mol.Biol., 388, 2009
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1MO4 | |
1MO5 | |
1W0D | | THE HIGH RESOLUTION STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LEUB (RV2995C) | | Descriptor: | 3-ISOPROPYLMALATE DEHYDROGENASE, SULFATE ION | | Authors: | Singh, R.K., Kefala, G., Janowski, R., Mueller-Dieckmann, C., Weiss, M.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2004-06-03 | | Release date: | 2004-12-14 | | Last modified: | 2019-08-21 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The High Resolution Structure of Leub (Rv2995C) from Mycobacterium Tuberculosis
J.Mol.Biol., 346, 2005
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3DHY | | CRYSTAL STRUCTURES OF MYCOBACTERIUM TUBERCULOSIS S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE IN TERNARY COMPLEX WITH SUBSTRATE AND INHIBITORS | | Descriptor: | Adenosylhomocysteinase, 5'-S-ethyl-5'-thioadenosine, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Shetty, N.D., Ioerger, T.R., Gokulan, K., Reddy, M.C.M., Owen, J.L., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-06-19 | | Release date: | 2008-09-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors.
Protein Sci., 17, 2008
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3MML | | ALLOPHANATE HYDROLASE COMPLEX FROM MYCOBACTERIUM SMEGMATIS, MSMEG0435-MSMEG0436 | | Descriptor: | Allophanate hydrolase subunit 2, Allophanate hydrolase subunit 1, CHLORIDE ION | | Authors: | Kaufmann, M., Chernishof, I., Shin, A., Germano, D., Sawaya, M.R., Waldo, G.S., Arbing, M.A., Perry, J., Eisenberg, D., Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2010-04-20 | | Release date: | 2010-04-28 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of Allphanate Hydrolase Complex from M. smegmatis, Msmeg0435-Msmeg0436
To be Published
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3QQS | | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE (TRPD) FROM MYCOBACTERIUM TUBERCULOSIS (COMPLEX WITH INHIBITOR ACS172) | | Descriptor: | Anthranilate phosphoribosyltransferase, ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID, MAGNESIUM ION, ... | | Authors: | Castell, A., Short, F.L., Lott, J.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2011-02-16 | | Release date: | 2012-08-22 | | Last modified: | 2014-01-01 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
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3QS8 | | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE (TRPD) FROM MYCOBACTERIUM TUBERCULOSIS (COMPLEX WITH INHIBITOR ACS174) | | Descriptor: | Anthranilate phosphoribosyltransferase, ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID, MAGNESIUM ION, ... | | Authors: | Castell, A., Short, F.L., Lott, J.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2011-02-20 | | Release date: | 2012-08-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
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3QSA | |
3R6C | | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE (TRPD) FROM MYCOBACTERIUM TUBERCULOSIS (COMPLEX WITH INHIBITOR ACS179) | | Descriptor: | Anthranilate phosphoribosyltransferase, ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID, MAGNESIUM ION, ... | | Authors: | Castell, A., Short, F.L., Lott, J.S., TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2011-03-21 | | Release date: | 2012-09-26 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
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3UNO | |
