2I3G
Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis in complex with NADP+.
Summary for 2I3G
| Entry DOI | 10.2210/pdb2i3g/pdb |
| Descriptor | N-acetyl-gamma-glutamyl-phosphate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total) |
| Functional Keywords | dimer interface beta sandwich, dimer, rossmann fold, structural genomics, mycobacterium tuberculosis structural proteomics project, xmtb, tb structural genomics consortium, tbsgc, oxidoreductase |
| Biological source | Mycobacterium tuberculosis |
| Cellular location | Cytoplasm (Probable): P63562 |
| Total number of polymer chains | 2 |
| Total formula weight | 74587.64 |
| Authors | Cherney, L.T.,Cherney, M.M.,Garen, C.R.,Moraidin, F.,James, M.N.G.,Mycobacterium Tuberculosis Structural Proteomics Project (XMTB),TB Structural Genomics Consortium (TBSGC) (deposition date: 2006-08-18, release date: 2006-09-05, Last modification date: 2023-08-30) |
| Primary citation | Cherney, L.T.,Cherney, M.M.,Garen, C.R.,Niu, C.,Moradian, F.,James, M.N.G. Crystal Structure of N-acetyl-gamma-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP(+). J.Mol.Biol., 367:1357-1369, 2007 Cited by PubMed: 17316682DOI: 10.1016/j.jmb.2007.01.033 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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