1C3V

DIHYDRODIPICOLINATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND PDC

Summary for 1C3V

Related1P9L
DescriptorDIHYDRODIPICOLINATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PYRIDINE-2,6-DICARBOXYLIC ACID, ... (5 entities in total)
Functional Keywordstwo-domain structure, tb structural genomics consortium, tbsgc, structural genomics, psi, protein structure initiative, oxidoreductase
Biological sourceMycobacterium tuberculosis
Total number of polymer chains2
Total molecular weight53606.07
Authors
Cirilli, M.,Zheng, R.,Scapin, G.,Blanchard, J.S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 1999-07-28, release date: 2003-08-26, Last modification date: 2017-10-04)
Primary citation
Cirilli, M.,Zheng, R.,Scapin, G.,Blanchard, J.S.
The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity
Biochemistry, 42:10644-10650, 2003
PubMed: 12962488 (PDB entries with the same primary citation)
DOI: 10.1021/bi030044v
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.39 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25090.4%10.6%3.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload