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4GKS
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BU of 4gks by Molmil
A2-MHC Complex carrying FLTGIGIITV
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, FLT Cognate peptide, ...
Authors:Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.346 Å)
Cite:T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
4GKN
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BU of 4gkn by Molmil
A2-MHC Complex carrying FATGIGIITV
Descriptor: Beta-2-microglobulin, FAT Cognate peptide, MHC class I antigen, ...
Authors:Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
5MEN
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BU of 5men by Molmil
Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MEQ
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BU of 5meq by Molmil
Human Leukocyte Antigen A02 presenting ILAKFLHTL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Cole, D.K, Lloyd, A, Crowther, M, Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MEP
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BU of 5mep by Molmil
Human Leukocyte Antigen A02 presenting ILGKFLHWL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Cole, D.K, Lloyd, A, Crowther, M, Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
7ZUC
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BU of 7zuc by Molmil
Human Major Histocompatibility Complex A2 allele presenting LLLGIGILV
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-LEU-LEU-GLY-ILE-GLY-ILE-LEU-VAL, ...
Authors:Rizkallah, P.J, Wall, A, Sewell, A.K, Fuller, A.
Deposit date:2022-05-12
Release date:2023-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7P3D
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BU of 7p3d by Molmil
MHC I A02 Allele presenting YLQPRTFLL
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-07-07
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
7P3E
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BU of 7p3e by Molmil
MHC I A02 Allele presenting YLQLRTFLL
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, IODIDE ION, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-07-07
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
7PBE
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BU of 7pbe by Molmil
Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Human T-cell Receptor YLQ36, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-08-02
Release date:2022-04-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
7Q9B
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BU of 7q9b by Molmil
MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-11-12
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7Q99
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BU of 7q99 by Molmil
MHC Class I A02 Allele presenting NLSALGIFST, in complex with Mel5 TCR
Descriptor: 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-11-12
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7Q98
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BU of 7q98 by Molmil
MHC Class I A02 Allele presenting NLSALGIFST
Descriptor: 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Sewell, A.K.
Deposit date:2021-11-12
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7Q9A
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BU of 7q9a by Molmil
MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR
Descriptor: Beta-2-microglobulin, GLYCEROL, Human Mel5 T Cell Receptor, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-11-12
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
5C0A
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BU of 5c0a by Molmil
1E6 TCR in complex with HLA-A02 carrying MVW peptide
Descriptor: 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ...
Authors:Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0J
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BU of 5c0j by Molmil
HLA-A02 carrying RQFGPDWIVA
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, CALCIUM ION, ...
Authors:Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0D
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BU of 5c0d by Molmil
HLA-A02 carrying AQWGPDPAAA
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
4GKZ
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BU of 4gkz by Molmil
HA1.7, a MHC class II restricted TCR specific for haemagglutinin
Descriptor: 1,2-ETHANEDIOL, Alpha chain of Class II TCR, Beta Chain of Class II TCR, ...
Authors:Holland, C.J, Rizkallah, P.J, Cole, D.K, Sewell, A.K, Godkin, A.J.
Deposit date:2012-08-13
Release date:2012-11-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers.
Sci Rep, 2, 2012
6G3J
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BU of 6g3j by Molmil
MHC A02 Allele presenting MTSAIGILVP
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Rizkallah, P.J, Sewell, A.K.
Deposit date:2018-03-26
Release date:2019-02-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Peptide Super-Agonist Enhances T-Cell Responses to Melanoma.
Front Immunol, 10, 2019
6G3K
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BU of 6g3k by Molmil
MHC A02 Allele presenting MTSAIGILPV
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Rizkallah, P.J, Sewell, A.K.
Deposit date:2018-03-26
Release date:2019-09-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Peptide Super-Agonist Enhances T-Cell Responses to Melanoma.
Front Immunol, 10, 2019
6HBY
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BU of 6hby by Molmil
HLA class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope
Descriptor: 1,2-ETHANEDIOL, ARRPPLAELAALNLSGSRL 5T4 tumour epitope, HLA class II histocompatibility antigen, ...
Authors:MacLachlan, B, Rizkallah, P.J, Sewell, A.K, Cole, D.K, Godkin, A.J.
Deposit date:2018-08-13
Release date:2019-08-14
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope.
J.Biol.Chem., 294, 2019
5MEO
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BU of 5meo by Molmil
Human Leukocyte Antigen presenting ILGKFLHRL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.772 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MER
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BU of 5mer by Molmil
Human Leukocyte Antigen A02 presenting ILAKFLHEL
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5NMK
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BU of 5nmk by Molmil
HLA A02 presenting SLFNTIAVL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-06
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NME
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BU of 5nme by Molmil
868 TCR in complex with HLA A02 presenting SLYNTVATL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMF
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BU of 5nmf by Molmil
868 TCR in complex with HLA A02 presenting SLYNTIATL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017

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