4GKS

A2-MHC Complex carrying FLTGIGIITV

Summary for 4GKS
Related4GKN
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, FLT Cognate peptide, ... (7 entities in total)
Functional Keywordsmajor histocompatibility complex, t-cell receptor, immuno, immunoglobulin, recognition, mhc, tcr, immune system
Biological sourceHomo sapiens (human)
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Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769
Total number of polymer chains6
Total formula weight90815.00
Authors
Sewell, A.K.,Rizkallah, P.J.,Cole, D.K.,Wooldridge, L.,Price, D.A. (deposition date: 2012-08-13, release date: 2012-09-12, Last modification date: 2012-11-14)
Primary citationBaker, B.M.,Baxter, T.K.,Clement, M.,Cole, D.K.,Dolton, G.M.,Edwards, E.S.,Ekeruche-Makinde, J.,Fuller, A.,Gostick, E.,Ladell, K.,Lissina, A.,Lloyd, K.A.,Madura, F.,Matthews, K.K.,Miles, J.J.,Pentier, J.,Price, D.A.,Rizkallah, P.J.,Sewell, A.K.,Wooldridge, L.
T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287:37269-37281, 2012
PubMed: 22952231
DOI: 110.1074/jbc.M112.386409
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.346 Å)
Structure validation
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PDB entries from 2021-06-23