Author results

3QL9
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MONOCLINIC COMPLEX STRUCTURE OF ATRX ADD BOUND TO HISTONE H3K9ME3 PEPTIDE
Descriptor:Transcriptional regulator ATRX, peptide of Histone H3.3, ZINC ION
Authors:Xiang, B., Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
1TJX
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CRYSTALLOGRAPHIC IDENTIFICATION OF CA2+ COORDINATION SITES IN SYNAPTOTAGMIN I C2B DOMAIN
Descriptor:similar to synaptotagminI/p65, CALCIUM ION, ACETATE ION, ...
Authors:Cheng, Y., Sequeira, S.M., Malinina, L., Tereshko, V., Sollner, T.H., Patel, D.J.
Deposit date:2004-06-07
Release date:2004-11-23
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain.
Protein Sci., 13, 2004
1UOW
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CALCIUM BINDING DOMAIN C2B
Descriptor:SYNAPTOTAGMIN I, CALCIUM ION, GLYCEROL, ...
Authors:Cheng, Y., Sequeira, S.M., Sollner, T.H., Patel, D.J.
Deposit date:2003-09-24
Release date:2004-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
3RZN
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CRYSTAL STRUCTURE OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH 3-O-SULFO-GALACTOSYLCERAMIDE CONTAINING NERVONOYL ACYL CHAIN (24:1)
Descriptor:Glycolipid transfer protein, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE
Authors:Samygina, V., Cabo-Bilbao, A., Popov, A.N., Ochoa-Lizarralde, B., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-12
Release date:2012-02-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
1TJM
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CRYSTALLOGRAPHIC IDENTIFICATION OF SR2+ COORDINATION SITE IN SYNAPTOTAGMIN I C2B DOMAIN
Descriptor:Synaptotagmin I, STRONTIUM ION, GLYCEROL
Authors:Cheng, Y., Sequeira, S.M., Malinina, L., Tereshko, V., Sollner, T.H., Patel, D.J.
Deposit date:2004-06-06
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain
Protein Sci., 13, 2004
4GH0
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide, PENTADECANE
Authors:Samygina, V.R., Cabo-Bilbao, A., Ochoa-Lizarralde, B., Popov, A.N., Malinina, L.
Deposit date:2012-08-07
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
3S0K
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CRYSTAL STRUCTURE OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH GLUCOSYLCERAMIDE CONTAINING OLEOYL ACYL CHAIN (18:1)
Descriptor:Glycolipid transfer protein, (9Z)-N-[(2S,3R,4E)-1-(beta-D-glucopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]octadec-9-enamide, NICKEL (II) ION
Authors:Cabo-Bilbao, A., Samygina, V., Popov, A.N., Ochoa-Lizarralde, B., Goni-de-Cerio, F., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-13
Release date:2012-02-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
2RI7
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CRYSTAL STRUCTURE OF PHD FINGER-LINKER-BROMODOMAIN Y17E MUTANT FROM HUMAN BPTF IN THE H3(1-9)K4ME2 BOUND STATE
Descriptor:Nucleosome-remodeling factor subunit BPTF, histone H3.1, ZINC ION, ...
Authors:Li, H., Patel, D.J.
Deposit date:2007-10-10
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
4H2Z
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide, PENTADECANE, ...
Authors:Samygina, V.R., Ochoa-Lizarralde, B., Malinina, L.
Deposit date:2012-09-13
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
5KDI
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HOW FAPP2 SELECTS SIMPLE GLYCOSPHINGOLIPIDS USING THE GLTP-FOLD
Descriptor:Pleckstrin homology domain-containing family A member 8, (~{Z})-~{N}-[(~{E},2~{S},3~{R})-1-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-octadec-4-en-2-yl]octadec-9-enamide
Authors:Ochoa-Lizarralde, B., Popov, A.N., Samygina, V.R., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2016-06-08
Release date:2017-12-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:How FAPP2 Selects Simple Glycosphingolipids Using the GLTP-fold: Structural Insights into Specificity in the GLTP-Family
J.Biol.Chem., 2017
2H6N
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HISTONE H3 RECOGNITION AND PRESENTATION BY THE WDR5 MODULE OF THE MLL1 COMPLEX
Descriptor:WD-repeat protein 5, Histone H3 K4-Me2 9-residue peptide
Authors:Ruthenburg, A.J., Wang, W.-K., Graybosch, D.M., Li, H., Allis, C.D., Patel, D.J., Verdine, G.L.
Deposit date:2006-05-31
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
3D2Q
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CRYSTAL STRUCTURE OF MBNL1 TANDEM ZINC FINGER 3 AND 4 DOMAIN
Descriptor:Muscleblind-like protein 1, ZINC ION
Authors:Teplova, M., Patel, D.J.
Deposit date:2008-05-08
Release date:2008-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Nat.Struct.Mol.Biol., 15, 2008
3QZT
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CRYSTAL STRUCTURE OF BPTF BROMO IN COMPLEX WITH HISTONE H4K16AC - FORM II
Descriptor:Nucleosome-remodeling factor subunit BPTF, Histone H4, GLYCEROL
Authors:Li, H., Ruthenburg, A.J., Patel, D.J.
Deposit date:2011-03-07
Release date:2011-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011
3RWV
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CRYSTAL STRUCTURE OF APO-FORM OF HUMAN GLYCOLIPID TRANSFER PROTEIN AT 1.5 A RESOLUTION
Descriptor:Glycolipid transfer protein, SULFATE ION
Authors:Samygina, V., Cabo-Bilbao, A., Popov, A.N., Ochoa-Lizarralde, B., Goni-de-Cerio, F., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-09
Release date:2012-02-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
3S0I
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH 3-O-SULFO GALACTOSYLCERAMIDE CONTAINING NERVONOYL ACYL CHAIN
Descriptor:Glycolipid transfer protein, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE
Authors:Samygina, V., Popov, A.N., Cabo-Bilbao, A., Ochoa-Lizarralde, B., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-13
Release date:2012-02-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
4MDX
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CRYSTAL STRUCTURE OF BACILLUS SUBTILIS MAZF IN COMPLEX WITH RNA
Descriptor:mRNA interferase EndoA, RNA, mRNA, ...
Authors:Simanshu, D.K., Patel, D.J.
Deposit date:2013-08-23
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis of mRNA Recognition and Cleavage by Toxin MazF and Its Regulation by Antitoxin MazE in Bacillus subtilis.
Mol.Cell, 52, 2013
4QUC
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CRYSTAL STRUCTURE OF CHROMODOMAIN OF RHINO
Descriptor:RE36324p
Authors:Li, S., Patel, D.J.
Deposit date:2014-07-10
Release date:2014-08-20
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing.
Genes Dev., 28, 2014
2OE5
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1.5 A X-RAY CRYSTAL STRUCTURE OF APRAMYCIN COMPLEX WITH RNA FRAGMENT GGCGUCGCUAGUACCG/GGUACUAAAAGUCGCCC CONTAINING THE HUMAN RIBOSOMAL DECODING A SITE: RNA CONSTRUCT WITH 3'-OVERHANG
Descriptor:RNA (5'-R(*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*CP*G)-3'), RNA (5'-R(*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*CP*C)-3'), SULFATE ION, ...
Authors:Hermann, T., Tereshko, V., Skripkin, E., Patel, D.J.
Deposit date:2006-12-28
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Apramycin recognition by the human ribosomal decoding site.
Blood Cells Mol.Dis., 38, 2007
3LD7
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CRYSTAL STRUCTURE OF THE LIN0431 PROTEIN FROM LISTERIA INNOCUA, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LKR112
Descriptor:Lin0431 protein
Authors:Vorobiev, S., Chen, Y., Lee, D., Patel, D.J., Ciccosanti, C., Sahdev, S., Acton, T.B., Xiao, R., Everett, J.K., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-01-12
Release date:2010-01-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.547 Å)
Cite:Crystal structure of the Lin0431 protein from Listeria innocua
To be Published
1OZ2
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CRYSTAL STRUCTURE OF 3-MBT REPEATS OF LETHAL (3) MALIGNANT BRAIN TUMOR (NATIVE-II) AT 1.55 ANGSTROM
Descriptor:Lethal(3)malignant brain tumor-like protein, SULFATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Wang, W.K., Tereshko, V., Boccuni, P., MacGrogan, D., Nimer, S.D., Patel, D.J.
Deposit date:2003-04-07
Release date:2003-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets.
Structure, 11, 2003
4IX7
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CRYSTAL STRUCTURE OF THE INSV-BEN DOMAIN COMPLEXED TO ITS DNA TARGET SITE
Descriptor:5'-D(*GP*TP*TP*CP*CP*AP*AP*TP*TP*GP*GP*AP*A)-3', RE55538p
Authors:Ren, A., Serganov, A., Patel, D.J.
Deposit date:2013-01-24
Release date:2013-03-20
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (1.581 Å)
Cite:The BEN domain is a novel sequence-specific DNA-binding domain conserved in neural transcriptional repressors.
Genes Dev., 27, 2013
3QLA
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HEXAGONAL COMPLEX STRUCTURE OF ATRX ADD BOUND TO H3K9ME3 PEPTIDE
Descriptor:Transcriptional regulator ATRX, peptide of Histone H3.3, ZINC ION, ...
Authors:Xiang, B., Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
4QXB
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CRYSTAL STRUCTURE OF HISTONE DEMETHYLASE KDM2A-H3K36ME3 WITH NOG
Descriptor:Lysine-specific demethylase 2A, Histone H3.2, N-OXALYLGLYCINE, ...
Authors:Cheng, Z.J., Patel, D.J.
Deposit date:2014-07-19
Release date:2014-11-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
5DAG
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CRYSTAL STRUCTURE OF PZP DOMAIN OF HUMAN AF10 PROTEIN
Descriptor:Protein AF-10, ZINC ION
Authors:Chen, S., Patel, D.J.
Deposit date:2015-08-19
Release date:2015-10-21
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
1SWX
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CRYSTAL STRUCTURE OF A HUMAN GLYCOLIPID TRANSFER PROTEIN IN APO-FORM
Descriptor:Glycolipid transfer protein, HEXANE
Authors:Malinina, L., Malakhova, M.L., Teplov, A., Brown, R.E., Patel, D.J.
Deposit date:2004-03-30
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for glycosphingolipid transfer specificity.
Nature, 430, 2004