3RAX

Dpo4 extension ternary complex with 3'-terminal primer T base opposite the 1-methylguanine (M1G) lesion

Summary for 3RAX

• Entry DOI: 10.2210/pdb3rax/pdb
• Related: 3RAQ
• Descriptor: DNA polymerase IV, DNA (5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DT))-3'), DNA (5'-D(*CP*CP*TP*AP*AP*CP*(MG1)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ... (6 entities in total)
• Functional Keywords: dna damage, dna repair, dna replication, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, transferase, transferase-dna complex, lesion bypass, dna polymerase, y-family polymerase, dntp binding, 1-methylguanine, transferase/dna
• Biological source: Sulfolobus solfataricus; More
• Cellular location: Cytoplasm (Probable): Q97W02
• Total number of polymer chains: 6
• Total formula weight: 99232.72

Authors

Rechkoblit, O.,Patel, D.J. (deposition date: 2011-03-28, release date: 2011-06-15, Last modification date: 2023-09-13)

• Primary citation: Rechkoblit, O.,Delaney, J.C.,Essigmann, J.M.,Patel, D.J.; Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.; Structure, 19:821-832, 2011; PubMed: 21645853; DOI: 10.1016/j.str.2011.03.020

Experimental method

X-RAY DIFFRACTION (1.891 Å)