134D

SOLUTION STRUCTURE OF A PURINE(DOT)PURINE(DOT)PYRIMIDINE DNA TRIPLEX CONTAINING G(DOT)GC AND T(DOT)AT TRIPLES

Summary for 134D

• Entry DOI: 10.2210/pdb134d/pdb
• Related: 135D 136D
• Descriptor: DNA TRIPLEX (1 entity in total)
• Functional Keywords: dna, triplex
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 9552.12

Authors

Patel, D.J.,Radhakrishnan, I. (deposition date: 1993-08-30, release date: 1994-04-30, Last modification date: 2024-04-10)

Primary citation

Radhakrishnan, I.,Patel, D.J.
Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples.
Structure, 1:135-152, 1993

PubMed Abstract: Oligonucleotide-directed triple helix formation allows sequence specific recognition of double helical DNA. This powerful approach has been used to inhibit gene transcription in vitro and to mediate single site specific cleavage of a human chromosome.

PubMed: 8069626
DOI: 10.1016/0969-2126(93)90028-F

Experimental method

SOLUTION NMR