3KHG
Dpo4 extension ternary complex with misinserted A opposite the 2-aminofluorene-guanine [AF]G lesion
Summary for 3KHG
Entry DOI | 10.2210/pdb3khg/pdb |
Related | 3KHH 3KHL 3KHR |
Descriptor | DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', 5'-D(*C*CP*TP*AP*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', ... (8 entities in total) |
Functional Keywords | lesion bypass, dna polymerase, y-family polymerase, 2-aminofluorene, semi-targeted mutagenesis, dna damage, dna repair, dna replication, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, transferase, transferase-dna complex, transferase/dna |
Biological source | Sulfolobus solfataricus P2 More |
Cellular location | Cytoplasm (Probable): Q97W02 |
Total number of polymer chains | 6 |
Total formula weight | 99245.10 |
Authors | Rechkoblit, O.,Malinina, L.,Patel, D.J. (deposition date: 2009-10-30, release date: 2010-02-16, Last modification date: 2023-09-06) |
Primary citation | Rechkoblit, O.,Kolbanovskiy, A.,Malinina, L.,Geacintov, N.E.,Broyde, S.,Patel, D.J. Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nat.Struct.Mol.Biol., 17:379-388, 2010 Cited by PubMed: 20154704DOI: 10.1038/nsmb.1771 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.96 Å) |
Structure validation
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