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3KHR

Dpo4 post-extension ternary complex with the correct C opposite the 2-aminofluorene-guanine [AF]G lesion

Summary for 3KHR
Entry DOI10.2210/pdb3khr/pdb
Related3KHG 3KHH 3KHL
DescriptorDNA polymerase IV, 5'-D(*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*CP*(DDG))-3', 5'-D(*CP*C*TP*AP*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', ... (7 entities in total)
Functional Keywordslesion bypass, dna polymerase, y-family polymerase, 2-aminofluorene, semi-targeted mutagenesis, dna damage, dna repair, dna replication, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, transferase, transferase-dna complex, transferase/dna
Biological sourceSulfolobus solfataricus P2
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Cellular locationCytoplasm (Probable): Q97W02
Total number of polymer chains6
Total formula weight98908.72
Authors
Rechkoblit, O.,Malinina, L.,Patel, D.J. (deposition date: 2009-10-30, release date: 2010-02-16, Last modification date: 2023-09-06)
Primary citationRechkoblit, O.,Kolbanovskiy, A.,Malinina, L.,Geacintov, N.E.,Broyde, S.,Patel, D.J.
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4.
Nat.Struct.Mol.Biol., 17:379-388, 2010
Cited by
PubMed: 20154704
DOI: 10.1038/nsmb.1771
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.01 Å)
Structure validation

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