Author results

6MUU
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CRYO-EM STRUCTURE OF CSM-CRRNA BINARY COMPLEX IN TYPE III-A CRISPR-CAS SYSTEM
Descriptor:Uncharacterized protein Csm1, Uncharacterized protein Csm2, Uncharacterized protein Csm3, ...
Authors:Jia, N., Wang, C., Eng, E.T., Patel, D.J.
Deposit date:2018-10-23
Release date:2018-12-19
Last modified:2019-01-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUT
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CRYO-EM STRUCTURE OF TERNARY CSM-CRRNA-TARGET RNA WITH ANTI-TAG SEQUENCE COMPLEX IN TYPE III-A CRISPR-CAS SYSTEM
Descriptor:Uncharacterized protein Csm1, Uncharacterized protein Csm2, Uncharacterized protein Csm3, ...
Authors:Jia, N., Wang, C., Eng, E.T., Patel, D.J.
Deposit date:2018-10-23
Release date:2018-12-12
Last modified:2019-01-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUS
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CRYO-EM STRUCTURE OF LARGER CSM-CRRNA-TARGET RNA TERNARY COMPLEX IN TYPE III-A CRISPR-CAS SYSTEM
Descriptor:Uncharacterized protein Csm1, Uncharacterized protein Csm2, Uncharacterized protein Csm3, ...
Authors:Jia, N., Wang, C., Eng, E.T.
Deposit date:2018-10-23
Release date:2018-12-12
Last modified:2019-01-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUR
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CRYO-EM STRUCTURE OF CSM-CRRNA-TARGET RNA TERNARY COMPLEX IN TYPE III-A CRISPR-CAS SYSTEM
Descriptor:Uncharacterized protein, Uncharacterized protein Csm3, RNA (27-MER), ...
Authors:Jia, N., Wang, C., Eng, E.T., Patel, D.J.
Deposit date:2018-10-23
Release date:2018-12-12
Last modified:2019-01-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUA
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CRYSTAL STRUCTURE OF CSM1-CSM4 SUBCOMPLEX IN THE TYPE III-A CRISPR-CSM INTERFERENCE COMPLEX
Descriptor:Uncharacterized protein Csm1, Uncharacterized protein Csm4
Authors:Jia, N., Patel, D.J.
Deposit date:2018-10-22
Release date:2019-01-09
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6J23
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CRYSTAL STRUCTURE OF ARABIDOPSIS ADAL COMPLEXED WITH GMP
Descriptor:Adenosine/AMP deaminase family protein, GUANOSINE-5'-MONOPHOSPHATE, ZINC ION
Authors:Wu, B.X., Zhang, D., Nie, H.B., Shen, S.L., Li, S.S., Patel, D.J.
Deposit date:2018-12-30
Release date:2019-02-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of arabidopsis N6-mAMP deaminase MAPDA
To Be Published
6IV5
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CRYSTAL STRUCTURE OF ARABIDOPSIS N6-MAMP DEAMINASE MAPDA
Descriptor:Adenosine/AMP deaminase family protein, PHOSPHATE ION, ZINC ION
Authors:Wu, B.X., Zhang, D., Nie, H.B., Shen, S.L., Li, S.S., Patel, D.J.
Deposit date:2018-12-02
Release date:2019-02-27
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Crystal structure of arabidopsis N6-mAMP deaminase MAPDA
To Be Published
6D9L
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TERNARY RSAGO COMPLEX WITH GUIDE RNA AND TARGET DNA CONTAINING G-A NON-CANONICAL PAIR
Descriptor:Uncharacterized protein, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*GP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*AP*GP*CP*AP*GP*TP*AP*AP*C)-3'), ...
Authors:Liu, Y., Esyunina, D., Olovnikov, I., Teplova, M., Patel, D.J.
Deposit date:2018-04-30
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6D9K
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TERNARY RSAGO COMPLEX WITH GUIDE RNA AND TARGET DNA CONTAINING A-G NON-CANONICAL PAIR
Descriptor:Uncharacterized protein, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*AP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*GP*GP*CP*AP*GP*TP*AP*AP*C)-3'), ...
Authors:Liu, Y., Esyunina, D., Olovnikov, I., Teplova, M., Patel, D.J.
Deposit date:2018-04-30
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6D95
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TERNARY RSAGO COMPLEX WITH GUIDE RNA PAIRED AND TARGET DNA CONTAINING A8-A8' NON-CANONICAL PAIR
Descriptor:Uncharacterized protein, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*AP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), DNA 24-Mer, ...
Authors:Liu, Y., Esyunina, D., Olovnikov, I., Teplova, M., Patel, D.J.
Deposit date:2018-04-27
Release date:2018-08-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6D92
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TERNARY RSAGO COMPLEX WITH GUIDE RNA AND TARGET DNA CONTAINING A-A NON-CANONICAL PAIR AT POSITION 3
Descriptor:Uncharacterized protein, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*AP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*AP*AP*AP*C)-3'), ...
Authors:Liu, Y., Esyunina, D., Olovnikov, I., Teplova, M., Patel, D.J.
Deposit date:2018-04-27
Release date:2018-07-25
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6D8P
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TERNARY RSAGO COMPLEX CONTAINING GUIDE RNA PAIRED WITH TARGET DNA
Descriptor:Uncharacterized protein, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*AP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*TP*AP*AP*C)-3'), ...
Authors:Liu, Y., Esyunina, D., Olovnikov, I., Teplova, M., Patel, D.J.
Deposit date:2018-04-26
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6D8F
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RSAGO TERNARY COMPLEX WITH GUIDE RNA AND TARGET DNA CONTAINING T-T BULGE WITHIN THE SEED SEGMENT
Descriptor:Uncharacterized protein, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*AP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*TP*TP*TP*AP*AP*C)-3'), ...
Authors:Liu, Y., Esyunina, D., Olovnikov, I., Teplova, M., Patel, D.J.
Deposit date:2018-04-26
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6D8A
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RSAGO TERNARY COMPLEX WITH GUIDE RNA AND TARGET DNA CONTAINING A-A BULGE WITHIN THE SEED SEGMENT OF THE TARGET STRAND
Descriptor:Uncharacterized protein, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*AP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*AP*AP*TP*AP*AP*C)-3'), ...
Authors:Liu, Y., Esyunina, D., Olovnikov, I., Teplova, M., Patel, D.J.
Deposit date:2018-04-26
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6B48
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF10
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B47
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF2
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B46
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF1
Descriptor:CRISPR-associated protein Csy3, Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B45
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B44
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND TARGET DSDNA
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2017-12-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6ANW
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CRYSTAL STRUCTURE OF ANTI-CRISPR PROTEIN ACRF10
Descriptor:anti-CRISPR protein AcrF10
Authors:Yang, H., Patel, D.J.
Deposit date:2017-08-14
Release date:2017-10-25
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6ANV
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CRYSTAL STRUCTURE OF ANTI-CRISPR PROTEIN ACRF1
Descriptor:anti-CRISPR protein AcrF1 fused with C-terminal MBP tag, MALTOTETRAOSE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Yang, H., Patel, D.J.
Deposit date:2017-08-14
Release date:2017-10-25
Method:X-RAY DIFFRACTION (2.265 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6AF0
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STRUCTURE OF CTR9, PAF1 AND CDC73 TERNARY COMPLEX FROM MYCELIOPHTHORA THERMOPHILA
Descriptor:Ctr9 protein, Paf1 protein, Cdc73 protein
Authors:Wang, Z., Deng, P., Zhou, Y.
Deposit date:2018-08-07
Release date:2018-09-19
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5Y87
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STRUCTURE-BASED INSIGHTS INTO SELF-CLEAVAGE BY A FOUR-WAY JUNCTIONAL TWISTER-SISTER RIBOZYME
Descriptor:RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3'), DNA/RNA (50-MER), MANGANESE (II) ION
Authors:Zheng, L., Micura, R.L., Ren, A.
Deposit date:2017-08-19
Release date:2017-11-22
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.132 Å)
Cite:Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
5Y85
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STRUCTURE-BASED INSIGHTS INTO SELF-CLEAVAGE BY A FOUR-WAY JUNCTIONAL TWISTER-SISTER RIBOZYME
Descriptor:RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3'), DNA/RNA (50-MER), MAGNESIUM ION
Authors:Zheng, L., Micura, R.L., Ren, A.
Deposit date:2017-08-18
Release date:2017-11-22
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
5Y6O
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CRYSTAL STRUCTURE OF DAXX N-TERMINAL FOUR-HELIX BUNDLE DOMAIN (4HB) IN COMPLEX WITH ATRX
Descriptor:Death domain-associated protein 6,Transcriptional regulator ATRX
Authors:Huang, H., Patel, D.J.
Deposit date:2017-08-13
Release date:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of DAXX N-terminal four-helix bundle domain (4HB) in complex with ATRX
Nat Commun, 2017