Author results

1TUB
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TUBULIN ALPHA-BETA DIMER, ELECTRON DIFFRACTION
分子名称:TUBULIN, GUANOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ...
著者Nogales, E., Downing, K.H.
登録日1997-09-23
公開日1998-10-07
最終更新日2011-07-13
実験手法ELECTRON CRYSTALLOGRAPHY (3.7 Å)
主引用文献Structure of the alpha beta tubulin dimer by electron crystallography.
Nature, 391, 1998
6CVJ
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MODEL OF SYNTHETIC TAU (FOUR TANDEM REPEATS OF FIRST REPEAT SEQUENCE) BOUND TO THE MICROTUBULE
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Microtubule-associated protein tau, ...
著者Nogales, E., Kellogg, E.H.
登録日2018-03-28
公開日2018-05-23
最終更新日2019-01-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Near-atomic model of microtubule-tau interactions.
Science, 360, 2018
6CVN
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MODEL OF SYNTHETIC TAU (R2X4) BOUND TO THE MICROTUBULE
分子名称:Tubulin beta chain, Tubulin alpha-1B chain, Microtubule-associated protein tau, ...
著者Nogales, E., Kellogg, E.H.
登録日2018-03-28
公開日2018-05-23
最終更新日2019-01-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Near-atomic model of microtubule-tau interactions.
Science, 360, 2018
1JFF
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REFINED STRUCTURE OF ALPHA-BETA TUBULIN FROM ZINC-INDUCED SHEETS STABILIZED WITH TAXOL
分子名称:tubulin alpha chain, tubulin beta chain, ZINC ION, ...
著者Lowe, J., Li, H., Downing, K.H., Nogales, E.
登録日2001-06-20
公開日2001-09-19
最終更新日2017-10-04
実験手法ELECTRON CRYSTALLOGRAPHY (3.5 Å)
主引用文献Refined structure of alpha beta-tubulin at 3.5 A resolution.
J.Mol.Biol., 313, 2001
4CMP
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CRYSTAL STRUCTURE OF S. PYOGENES CAS9
分子名称:CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, SULFATE ION, MAGNESIUM ION
著者Jinek, M., Jiang, F., Taylor, D.W., Sternberg, S.H., Kaya, E., Ma, E., Anders, C., Hauer, M., Zhou, K., Lin, S., Kaplan, M., Iavarone, A.T., Charpentier, E., Nogales, E., Doudna, J.A.
登録日2014-01-16
公開日2014-02-12
最終更新日2014-03-26
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014
4CMQ
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CRYSTAL STRUCTURE OF MN-BOUND S.PYOGENES CAS9
分子名称:CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION
著者Jinek, M., Jiang, F., Taylor, D.W., Sternberg, S.H., Kaya, E., Ma, E., Anders, C., Hauer, M., Zhou, K., Lin, S., Kaplan, M., Iavarone, A.T., Charpentier, E., Nogales, E., Doudna, J.A.
登録日2014-01-17
公開日2014-02-12
最終更新日2014-03-26
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
6B5B
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CRYO-EM STRUCTURE OF THE NAIP5-NLRC4-FLAGELLIN INFLAMMASOME
分子名称:Baculoviral IAP repeat-containing protein 1e, NLR family CARD domain-containing protein 4, Flagellin
著者Tenthorey, J.L., Haloupek, N., Lopez-Blanco, J.R., Grob, P., Adamson, E., Hartenian, E., Lind, N.A., Bourgeois, N.M., Chacon, P., Nogales, E., Vance, R.E.
登録日2017-09-29
公開日2017-11-15
最終更新日2017-12-06
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.
Science, 358, 2017
5KMG
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NEAR-ATOMIC CRYO-EM STRUCTURE OF PRC1 BOUND TO THE MICROTUBULE
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Protein regulator of cytokinesis 1, ...
著者Kellogg, E.H., Howes, S., Ti, S.-C., Ramirez-Aportela, E., Kapoor, T.M., Chacon, P., Nogales, E.
登録日2016-06-27
公開日2016-08-03
最終更新日2017-09-27
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Near-atomic cryo-EM structure of PRC1 bound to the microtubule.
Proc.Natl.Acad.Sci.USA, 113, 2016
6NY1
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CASX-GRNA-DNA(30BP) STATE II
分子名称:CasX, DNA Non-target strand, gRNA, ...
著者Liu, J.J., Orlova, N., Nogales, E., Doudna, J.A.
登録日2019-02-10
公開日2019-02-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
6NY2
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CASX-GRNA-DNA(45BP) STATE I
分子名称:DNA target strand, DNA Non-target strand, CasX, ...
著者Liu, J.J., Orlova, N., Nogales, E., Doudna, J.A.
登録日2019-02-10
公開日2019-02-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
6NY3
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CASX TERNARY COMPLEX WITH 30BP TARGET DNA
分子名称:DNA target strand, DNA Non-target strand, CasX, ...
著者Liu, J.J., Orlova, N., Nogales, E., Doudna, J.A.
登録日2019-02-10
公開日2019-02-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
3IZ0
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HUMAN NDC80 BONSAI DECORATED MICROTUBULE
分子名称:alpha tubulin, Chain A from PDB 1JFF, beta tubulin, ...
著者Alushin, G.M., Ramey, V.H., Pasqualato, S., Ball, D.A., Grigorieff, N., Musacchio, A., Nogales, E.
登録日2010-08-09
公開日2010-10-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献The Ndc80 kinetochore complex forms oligomeric arrays along microtubules.
Nature, 467, 2010
3J0K
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ORIENTATION OF RNA POLYMERASE II WITHIN THE HUMAN VP16-MEDIATOR-POL II-TFIIF ASSEMBLY
分子名称:DNA-directed RNA polymerase II largest subunit, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 45 kDa polypeptide, ...
著者Bernecky, C., Grob, P., Ebmeier, C.C., Nogales, E., Taatjes, D.J.
登録日2011-10-04
公開日2011-10-19
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (36 Å)
主引用文献Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly.
Plos Biol., 9, 2011
3J6E
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ENERGY MINIMIZED AVERAGE STRUCTURE OF MICROTUBULES STABILIZED BY GMPCPP
分子名称:Tubulin alpha-1A chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Alushin, G.M., Lander, G.C., Kellogg, E.H., Zhang, R., Baker, D., Nogales, E.
登録日2014-02-18
公開日2014-06-04
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
3J6F
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MINIMIZED AVERAGE STRUCTURE OF GDP-BOUND DYNAMIC MICROTUBULES
分子名称:Tubulin alpha-1A chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Alushin, G.M., Lander, G.C., Kellogg, E.H., Zhang, R., Baker, D., Nogales, E.
登録日2014-02-19
公開日2014-06-04
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
3J6G
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MINIMIZED AVERAGE STRUCTURE OF MICROTUBULES STABILIZED BY TAXOL
分子名称:Tubulin alpha-1A chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Alushin, G.M., Lander, G.C., Kellogg, E.H., Zhang, R., Baker, D., Nogales, E.
登録日2014-02-19
公開日2014-06-04
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
3JAK
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CRYO-EM STRUCTURE OF GTPGAMMAS-MICROTUBULE CO-POLYMERIZED WITH EB3 (MERGED DATASET WITH AND WITHOUT KINESIN BOUND)
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Microtubule-associated protein RP/EB family member 3, ...
著者Zhang, R., Nogales, E.
登録日2015-06-16
公開日2015-08-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
3JAL
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CRYO-EM STRUCTURE OF GMPCPP-MICROTUBULE CO-POLYMERIZED WITH EB3
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Microtubule-associated protein RP/EB family member 3, ...
著者Zhang, R., Nogales, E.
登録日2015-06-16
公開日2015-08-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
3JAR
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CRYO-EM STRUCTURE OF GDP-MICROTUBULE CO-POLYMERIZED WITH EB3
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Microtubule-associated protein RP/EB family member 3, ...
著者Zhang, R., Nogales, E.
登録日2015-06-19
公開日2015-08-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
3JAS
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CRYO-EM STRUCTURE OF DYNAMIC GDP-MICROTUBULE (14 PROTOFILAMENTS) DECORATED WITH KINESIN
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, R., Nogales, E.
登録日2015-06-19
公開日2015-08-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
3JAT
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CRYO-EM STRUCTURE OF GMPCPP-MICROTUBULE (14 PROTOFILAMENTS) DECORATED WITH KINESIN
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, R., Nogales, E.
登録日2015-06-20
公開日2015-08-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
3JAW
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ATOMIC MODEL OF A MICROTUBULE SEAM BASED ON A CRYO-EM RECONSTRUCTION OF THE EB3-BOUND MICROTUBULE (MERGED DATASET CONTAINING TUBULIN BOUND TO GTPGAMMAS, GMPCPP, AND GDP)
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, R., Nogales, E.
登録日2015-06-30
公開日2015-08-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
4BK0
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CRYSTAL STRUCTURE OF THE KIX DOMAIN OF HUMAN RECQL5 (DOMAIN-SWAPPED DIMER)
分子名称:ATP-DEPENDENT DNA HELICASE Q5, DI(HYDROXYETHYL)ETHER
著者Kassube, S.A., Jinek, M., Fang, J., Tsutakawa, S., Nogales, E.
登録日2013-04-21
公開日2013-06-12
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Mimicry in Transcription Regulation of Human RNA Polymerase II by the DNA Helicase Recql5
Nat.Struct.Mol.Biol., 20, 2013
5FUR
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STRUCTURE OF HUMAN TFIID-IIA BOUND TO CORE PROMOTER DNA
分子名称:TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2, ...
著者Louder, R.K., He, Y., Lopez-Blanco, J.R., Fang, J., Chacon, P., Nogales, E.
登録日2016-01-29
公開日2016-04-06
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly.
Nature, 531, 2016
5IJ0
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CRYO EM DENSITY OF MICROTUBULE ASSEMBLED FROM HUMAN TUBB3
分子名称:Tubulin alpha-1B chain, Tubulin beta-3 chain, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ti, S.-C., Pamula, M.C., Howes, S.C., Duellberg, C., Nicholas, C.I., Kleiner, R.E., Forth, S., Surrey, T., Nogales, E., Kapoor, T.M.
登録日2016-03-01
公開日2016-04-20
最終更新日2017-09-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends.
Dev.Cell, 37, 2016
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