5OF4

The cryo-EM structure of human TFIIH

Summary for 5OF4

• Entry DOI: 10.2210/pdb5of4/pdb
• EMDB information: 3802
• Descriptor: TFIIH basal transcription factor complex helicase XPB subunit,XPB,TFIIH basal transcription factor complex helicase XPB subunit, Unassigned secondary structure elements (XPB NTE region), IRON/SULFUR CLUSTER, ... (11 entities in total)
• Functional Keywords: transcription initiation, dna repair, multiprotein complex, kinase, helicase, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 306618.26

Authors

Greber, B.J.,Nguyen, T.H.D.,Fang, J.,Afonine, P.V.,Adams, P.D.,Nogales, E. (deposition date: 2017-07-10, release date: 2017-09-13, Last modification date: 2022-03-30)

• Primary citation: Greber, B.J.,Nguyen, T.H.D.,Fang, J.,Afonine, P.V.,Adams, P.D.,Nogales, E.; The cryo-electron microscopy structure of human transcription factor IIH.; Nature, 549:414-417, 2017; PubMed: 28902838; DOI: 10.1038/nature23903

Experimental method

ELECTRON MICROSCOPY (4.4 Å)