Author results

2VLJ
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THE STRUCTURAL DYNAMICS AND ENERGETICS OF AN IMMUNODOMINANT T-CELL RECEPTOR ARE PROGRAMMED BY ITS VBETA DOMAIN
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Ishizuka, J., Stewart-Jones, G., Van Der Merwe, A., Bell, J., Mcmichael, A., Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
2VLK
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THE STRUCTURAL DYNAMICS AND ENERGETICS OF AN IMMUNODOMINANT T-CELL RECEPTOR ARE PROGRAMMED BY ITS VBETA DOMAIN
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Ishizuka, J., Stewart-Jones, G., Van Der Merwe, A., Bell, J., Mcmichael, A., Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
2VLL
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THE STRUCTURAL DYNAMICS AND ENERGETICS OF AN IMMUNODOMINANT T-CELL RECEPTOR ARE PROGRAMMED BY ITS VBETA DOMAIN
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Ishizuka, J., Stewart-Jones, G., Van Der Merwe, A., Bell, J., Mcmichael, A., Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
2VLM
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THE STRUCTURAL DYNAMICS AND ENERGETICS OF AN IMMUNODOMINANT T-CELL RECEPTOR ARE PROGRAMMED BY ITS VBETA DOMAIN
Descriptor:JM22 TCR ALPHA CHAIN, JM22 TCR BETA CHAIN
Authors:Ishizuka, J., Stewart-Jones, G., Van der Merwe, A., Bell, J., McMichael, A., Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
2VLR
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THE STRUCTURAL DYNAMICS AND ENERGETICS OF AN IMMUNODOMINANT T-CELL RECEPTOR ARE PROGRAMMED BY ITS VBETA DOMAIN
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Ishizuka, J., Stewart-Jones, G., van der Merwe, A., Bell, J., McMichael, A., Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
1RT1
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH MKC-442
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, 6-BENZYL-1-ETHOXYMETHYL-5-ISOPROPYL URACIL
Authors:Ren, J., Esnouf, R., Hopkins, A., Willcox, B., Jones, Y., Ross, C., Stammers, D., Stuart, D.
Deposit date:1996-03-16
Release date:1997-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.
J.Med.Chem., 39, 1996
1RT2
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH TNK-651
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL
Authors:Ren, J., Esnouf, R., Hopkins, A., Willcox, B., Jones, Y., Ross, C., Stammers, D., Stuart, D.
Deposit date:1996-03-16
Release date:1997-04-21
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.
J.Med.Chem., 39, 1996
1REV
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HIV-1 REVERSE TRANSCRIPTASE
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, MAGNESIUM ION, 4-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE
Authors:Ren, J., Esnouf, R., Hopkins, A., Ross, C., Jones, Y., Stammers, D., Stuart, D.
Deposit date:1995-09-17
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design.
Structure, 3, 1995
1RTH
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HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT-INHIBITOR COMPLEXES
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, 6,11-DIHYDRO-11-ETHYL-6-METHYL-9-NITRO-5H-PYRIDO[2,3-B][1,5]BENZODIAZEPIN-5-ONE
Authors:Ren, J., Esnouf, R., Garman, E., Somers, D., Ross, C., Kirby, I., Keeling, J., Darby, G., Jones, Y., Stuart, D., Stammers, D.
Deposit date:1995-05-03
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High resolution structures of HIV-1 RT from four RT-inhibitor complexes.
Nat.Struct.Biol., 2, 1995
1RTI
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HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT-INHIBITOR COMPLEXES
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, 1-(2-HYDROXYETHYLOXYMETHYL)-6-PHENYL THIOTHYMINE
Authors:Ren, J., Esnouf, R., Garman, E., Somers, D., Ross, C., Kirby, I., Keeling, J., Darby, G., Jones, Y., Stuart, D., Stammers, D.
Deposit date:1995-05-03
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:High resolution structures of HIV-1 RT from four RT-inhibitor complexes.
Nat.Struct.Biol., 2, 1995
1RTJ
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MECHANISM OF INHIBITION OF HIV-1 REVERSE TRANSCRIPTASE BY NON-NUCLEOSIDE INHIBITORS
Descriptor:HIV-1 REVERSE TRANSCRIPTASE
Authors:Ren, J., Esnouf, R., Ross, C., Jones, Y., Stammers, D., Stuart, D.
Deposit date:1995-05-03
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors.
Nat.Struct.Biol., 2, 1995
1VRT
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HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT-INHIBITOR COMPLEXES
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, MAGNESIUM ION, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE
Authors:Ren, J., Esnouf, R., Garman, E., Somers, D., Ross, C., Kirby, I., Keeling, J., Darby, G., Jones, Y., Stuart, D., Stammers, D.
Deposit date:1995-04-19
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High resolution structures of HIV-1 RT from four RT-inhibitor complexes.
Nat.Struct.Biol., 2, 1995
1VRU
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HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT-INHIBITOR COMPLEXES
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, ALPHA-(2,6-DICHLOROPHENYL)-ALPHA-(2-ACETYL-5-METHYLANILINO)ACETAMIDE
Authors:Ren, J., Esnouf, R., Garman, E., Somers, D., Ross, C., Kirby, I., Keeling, J., Darby, G., Jones, Y., Stuart, D., Stammers, D.
Deposit date:1995-04-19
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:High resolution structures of HIV-1 RT from four RT-inhibitor complexes.
Nat.Struct.Biol., 2, 1995
1RT3
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AZT DRUG RESISTANT HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH 1051U91
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, 6,11-DIHYDRO-11-ETHYL-6-METHYL-9-NITRO-5H-PYRIDO[2,3-B][1,5]BENZODIAZEPIN-5-ONE
Authors:Ren, J., Stammers, D.K., Stuart, D.I.
Deposit date:1998-06-29
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes.
Proc.Natl.Acad.Sci.USA, 95, 1998
1RT4
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HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC781
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION, 2-METHYL-FURAN-3-CARBOTHIOIC ACID [4-CHLORO-3-(3-METHYL-BUT-2-ENYLOXY)-PHENYL]-AMIDE
Authors:Ren, J., Stammers, D.K., Stuart, D.I.
Deposit date:1998-07-29
Release date:1999-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.
Biochemistry, 37, 1998
1RT5
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HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC10
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION, N-[4-CLORO-3-(T-BUTYLOXOME)PHENYL-2-METHYL-3-FURAN-CARBOTHIAMIDE
Authors:Ren, J., Stammers, D.K., Stuart, D.I.
Deposit date:1998-07-29
Release date:1999-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.
Biochemistry, 37, 1998
1RT6
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HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC38
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION, 1-METHYL ETHYL 2-CHLORO-5-[[[(1-METHYLETHOXY)THIOOXO]METHYL]AMINO]-BENZOATE
Authors:Ren, J., Stammers, D.K., Stuart, D.I.
Deposit date:1998-07-29
Release date:1999-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.
Biochemistry, 37, 1998
1RT7
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HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC84
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION, 1-METHYL ETHYL 1-CHLORO-5-[[(5,6DIHYDRO-2-METHYL-1,4-OXATHIIN-3-YL)CARBONYL]AMINO]BENZOATE
Authors:Ren, J., Stammers, D.K., Stuart, D.I.
Deposit date:1998-07-29
Release date:1999-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.
Biochemistry, 37, 1998
1DTQ
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-1 (PETT131A94)
Descriptor:HIV-1 RT A-CHAIN, HIV-1 RT B-CHAIN, N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-NITRILOMETHYL-PYRIDYL]-THIOUREA
Authors:Ren, J., Diprose, J., Warren, J., Esnouf, R.M., Bird, L.E., Ikemizu, S., Slater, M., Milton, J., Balzarini, J., Stuart, D.I., Stammers, D.K.
Deposit date:2000-01-13
Release date:2000-03-20
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
J.Biol.Chem., 275, 2000
1DTT
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-2 (PETT130A94)
Descriptor:HIV-1 RT A-CHAIN, HIV-1 RT B-CHAIN, N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-CHLORO-PYRIDYL]-THIOUREA
Authors:Ren, J., Diprose, J., Warren, J., Esnouf, R.M., Bird, L.E., Ikemizu, S., Slater, M., Milton, J., Balzarini, J., Stuart, D.I., Stammers, D.K.
Deposit date:2000-01-13
Release date:2000-04-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
J.Biol.Chem., 275, 2000
1KLM
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HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH BHAP U-90152
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, (1-(5-METHANSULPHONAMIDO-1H-INDOL-2-YL-CARBONYL)4-[METHYLAMINO)PYRIDINYL]PIPERAZINE
Authors:Ren, J., Esnouf, R.M., Stammers, D.K., Stuart, D.I.
Deposit date:1997-03-17
Release date:1998-03-18
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor.
Proc.Natl.Acad.Sci.USA, 94, 1997
3BEV
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11MER STRUCTURE OF AN MHC CLASS I MOLECULE FROM B21 CHICKENS ILLUSTRATE PROMISCUOUS PEPTIDE BINDING
Descriptor:Major histocompatibility complex class I glycoprotein haplotype B21, Beta-2-microglobulin, Hemoglobin subunit alpha-A
Authors:Koch, M., Kaufman, J., Jones, Y.
Deposit date:2007-11-20
Release date:2008-01-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of an MHC class I molecule from b21 chickens illustrate promiscuous Peptide binding
Immunity, 27, 2007
3V81
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) WITH DNA AND THE NONNUCLEOSIDE INHIBITOR NEVIRAPINE
Descriptor:HIV-1 Reverse Transcriptase P66 subunit, HIV-1 Reverse Transcriptase P51 subunit, DNA (5'-D(*AP*TP*GP*GP*AP*AP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), ...
Authors:Das, K., Martinez, S.E., Arnold, E.
Deposit date:2011-12-22
Release date:2012-01-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8503 Å)
Cite:HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism.
Nat.Struct.Mol.Biol., 19, 2012