1RT6

HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC38

Summary for 1RT6
DescriptorHIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION, 1-METHYL ETHYL 2-CHLORO-5-[[[(1-METHYLETHOXY)THIOOXO]METHYL]AMINO]-BENZOATE, ... (5 entities in total)
Functional Keywordsnucleotidyltransferase, hiv-1 reverse transcriptase, aids, nonnucleoside inhibition, drug design
Biological sourceHIV-1 M:B_HXB2R
More
Cellular locationMatrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585 P04585
Total number of polymer chains2
Total formula weight116404.78
Authors
Ren, J.,Stammers, D.K.,Stuart, D.I. (deposition date: 1998-07-29, release date: 1999-07-29, Last modification date: 2011-07-13)
Primary citationBalzarini, J.,Esnouf, R.M.,Hopkins, A.L.,Ren, J.,Stammers, D.K.,Stuart, D.I.,Warren, J.
Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.
Biochemistry, 37:14394-14403, 1998
PubMed: 9772165
DOI: 110.1021/bi981309m
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation
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PDB entries from 2021-06-09