1REV

HIV-1 REVERSE TRANSCRIPTASE

Summary for 1REV

• Entry DOI: 10.2210/pdb1rev/pdb
• Descriptor: HIV-1 REVERSE TRANSCRIPTASE, MAGNESIUM ION, 4-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE, ... (5 entities in total)
• Functional Keywords: aids, polyprotein, hydrolase, aspartyl protease, endonuclease, nucleotidyltransferase, hiv-1 reverse transcriptase
• Biological source: Human immunodeficiency virus 1; More
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585 P04585
• Total number of polymer chains: 2
• Total formula weight: 116340.17

Authors

Ren, J.,Esnouf, R.,Hopkins, A.,Ross, C.,Jones, Y.,Stammers, D.,Stuart, D. (deposition date: 1995-09-17, release date: 1996-10-14, Last modification date: 2011-07-13)

• Primary citation: Ren, J.,Esnouf, R.,Hopkins, A.,Ross, C.,Jones, Y.,Stammers, D.,Stuart, D.; The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design.; Structure, 3:915-926, 1995; PubMed: 8535785; DOI: 10.1016/S0969-2126(01)00226-X

Experimental method

X-RAY DIFFRACTION (2.6 Å)