2VLR

The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain

Summary for 2VLR

Related1UQS 1BD2 2AK4 1YPZ 1IM3 1UXW 1I7U 1C16 1HSA 2AXF 1GZP 2BNQ 1W72 2JCC 2BCK 1DE4 1N2R 2VLK 1EXU 1QRN 2HLA 1MHE 1IM9 1EEZ 1JHT 1QQD 1QR1 1ZS8 1HLA 1JGD 1I1Y 1VGK 1AGE 1UR7 1S9X 1HHG 1A9E 1DUZ 2CLR 3HLA 1M05 1TVB 2V2W 1ONQ 1A1N 1LP9 1ZSD 1M6O 2BSU 1HHK 1ZT4 1HSB 1X7Q 1CE6 1PY4 1SYV 2J8U 1SYS 1OGT 1CG9 1P7Q 1Q94 1JNJ 1AGB 2D31 1AQD 1XZ0 1LDS 1HHH 1TVH 1XR8 2BSS 1A1M 1E28 2V2X 1XR9 2GJ6 1EFX 1QLF 2AV1 1TMC 1QSF 1DUY 1JGE 1KPR 2HJL 1QEW 1W0V 1K5N 1AO7 2BNR 1XH3 2BST 1MI5 2H26 1S9Y 1A1O 1AGF 2A83 1OGA 2F8O 2BSV 2CII 1I7R 1JF1 2C7U 2F74 1E27 1W0W 1GZQ 1UXS 1AKJ 2HJK 2VB5 1AGD 1R3H 1EEY 1I7T 1I4F 1YDP 2VLL 2BSR 2VLJ 1B0G 1B0R 1OF2 1HHI 1QSE 1A9B 2AXG 2BVQ 1AGC 1HHJ 1QVO 1S9W 1KTL 1A6Z 2CIK 2UWE 1I1F 2AV7 2VLM
DescriptorHLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, ... (6 entities in total)
Functional Keywordsimmune system, glycoprotein, transmembrane, immune system-receptor-complex, immunoglobulin domain, host-virus interaction, pyrrolidone carboxylic acid, immune response, immunodominance, disease mutation, membrane, secreted, receptor, glycation, tcr, flu, mhc, mhc i, t-cell, complex
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationMembrane; Single-pass type I membrane protein P01892
Secreted P61769
Total number of polymer chains10
Total molecular weight189182.29
Authors
Ishizuka, J.,Stewart-Jones, G.,van der Merwe, A.,Bell, J.,McMichael, A.,Jones, Y. (deposition date: 2008-01-15, release date: 2008-01-22, Last modification date: 2011-07-13)
Primary citation
Ishizuka, J.,Stewart-Jones, G.,Van Der Merwe, A.,Bell, J.,Mcmichael, A.,Jones, Y.
The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28:171-, 2008
PubMed: 18275829 (PDB entries with the same primary citation)
DOI: 10.1016/J.IMMUNI.2007.12.018
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27471.1%7.4%14.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution